Max Lugavere

As I mentioned, you want to not be a type two diabetic.

We know clearly that there's a vascular component to Alzheimer's disease.

So you want to make sure that you don't have hypertension.

That's very important.

You don't want to be obese.

Obesity increases your risk for hypertension.

It also increases your risk for insulin resistance and type two diabetes.

So you don't want to be obese.

There's actually an inverse correlation between

the size of your waist and total brain volume.

So as your waist expands, it seems that your brain shrinks.

The direction of causality isn't there.

It's just a correlation.

But nonetheless, visceral fat is strongly linked to insulin resistance and inflammation.

And the brain sits directly downwind of insulin resistance and inflammation, unfortunately.

Because I think they're looking for the cure in the wrong place.

They're trying to treat a condition that begins in the brain decades prior to the onset of symptoms.

And their target of approach is reducing amyloid in the brain.

And amyloid appears late, as we mentioned.

So, you know, by the time a person is diagnosed with Alzheimer's disease, glucose metabolism is already diminished by 50%.