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Max Lugavere

๐Ÿ‘ค Speaker
8803 total appearances

Appearances Over Time

Podcast Appearances

The Genius Life
AMA 4: Non-Negotiables for Brain Health, Top Evidence-Based Supplements, and Early Decline Warning Signs

And so what the study found was that specifically for people with elevated homocysteine, that supplementing with the B complex by up to 50% reduced shrinkage of the brain, reduced the rate of atrophy of the brain.

The Genius Life
AMA 4: Non-Negotiables for Brain Health, Top Evidence-Based Supplements, and Early Decline Warning Signs

Now, this effect was modified by people that had good omega-3 status.

The Genius Life
AMA 4: Non-Negotiables for Brain Health, Top Evidence-Based Supplements, and Early Decline Warning Signs

So that's important.

The Genius Life
AMA 4: Non-Negotiables for Brain Health, Top Evidence-Based Supplements, and Early Decline Warning Signs

And the effect was also dependent on whether or not they had high homocysteine levels.

The Genius Life
AMA 4: Non-Negotiables for Brain Health, Top Evidence-Based Supplements, and Early Decline Warning Signs

So this is all, again, there is no one size fits all.

The Genius Life
AMA 4: Non-Negotiables for Brain Health, Top Evidence-Based Supplements, and Early Decline Warning Signs

This is precision nutrition we're talking about.

The Genius Life
AMA 4: Non-Negotiables for Brain Health, Top Evidence-Based Supplements, and Early Decline Warning Signs

So if you go and get your labs drawn, you have high levels of homocysteine, you can take a B complex.

The Genius Life
AMA 4: Non-Negotiables for Brain Health, Top Evidence-Based Supplements, and Early Decline Warning Signs

Chances are you'll see your homocysteine levels drop.

The Genius Life
AMA 4: Non-Negotiables for Brain Health, Top Evidence-Based Supplements, and Early Decline Warning Signs

This occurred with me.

The Genius Life
AMA 4: Non-Negotiables for Brain Health, Top Evidence-Based Supplements, and Early Decline Warning Signs

I had a, I think it was like a homocysteine of...

The Genius Life
AMA 4: Non-Negotiables for Brain Health, Top Evidence-Based Supplements, and Early Decline Warning Signs

I don't know, like 11.

The Genius Life
AMA 4: Non-Negotiables for Brain Health, Top Evidence-Based Supplements, and Early Decline Warning Signs

It came down with, you know, after a couple of months of taking B vitamins to like six or seven.

The Genius Life
AMA 4: Non-Negotiables for Brain Health, Top Evidence-Based Supplements, and Early Decline Warning Signs

High homocysteine is a risk factor for Alzheimer's disease, for cardiovascular disease.

The Genius Life
AMA 4: Non-Negotiables for Brain Health, Top Evidence-Based Supplements, and Early Decline Warning Signs

And so what the study, the Vitacog study found was that for people with high homocysteine levels, taking a B complex lowered homocysteine led to a reduced atrophy rate of the brain.

The Genius Life
AMA 4: Non-Negotiables for Brain Health, Top Evidence-Based Supplements, and Early Decline Warning Signs

and also coincided with clinically meaningful improvement in cognitive function, which is great.

The Genius Life
AMA 4: Non-Negotiables for Brain Health, Top Evidence-Based Supplements, and Early Decline Warning Signs

So again, not one size fits all.

The Genius Life
AMA 4: Non-Negotiables for Brain Health, Top Evidence-Based Supplements, and Early Decline Warning Signs

If you have high homocysteine, consider a B complex.

The Genius Life
AMA 4: Non-Negotiables for Brain Health, Top Evidence-Based Supplements, and Early Decline Warning Signs

And that was the VITA-COG trial.

The Genius Life
AMA 4: Non-Negotiables for Brain Health, Top Evidence-Based Supplements, and Early Decline Warning Signs

Crucially, crucially important stuff.

The Genius Life
AMA 4: Non-Negotiables for Brain Health, Top Evidence-Based Supplements, and Early Decline Warning Signs

And then most recently, I think good data came out supporting the use of a multivitamin for older adults at risk for cognitive decline.