Meg Tirrell

I think that can be problematic.

Yeah, and the tolerance idea is totally fascinating too, which is something that I've talked to addiction researchers about because they're wondering, do you reach a level of tolerance of these medications now?

You need to keep taking them in order to keep staving off your addictions.

I think it's fascinating.

So you do have to titrate up on the medicines over time, mainly to try to ensure the tolerability is manageable.

So you start at the slow dose.

After a month, typically, you go to the next dose.

And sometimes people can stay at a certain dose, and that works for them.

Some people have to get to the highest dose and stay there.

We do see that there typically is a plateau.

People stop losing weight at a certain point with these medications.

They don't just lose and lose and lose.

And, you know, sometimes that might happen before somebody's lost as much weight as they want to lose.

I also hear from doctors that some people want to lose an unhealthy amount of weight.

And so then the doctors are having these conversations like, hey, you know,

I know you you weighed 105 pounds in college or whatever, but that doesn't mean you should weigh that now.

And so trying to have those conversations, too, about what's healthy and what's not.

But, yeah, people typically do seem to get used to the side effects and then you go up again and you might experience them again.

Yeah.

I mean, there can be other side effects, like people sometimes have hair loss.