Michael Regilio
๐ค SpeakerAppearances Over Time
Podcast Appearances
Of course, you're right. And it is super interesting. And it does, by the way, have to do with hair regrowth. incredibly rare everywhere on earth except one small village in the Dominican Republic called Salinas. In Salinas, one out of 90 boys are born with this condition.
Of course, you're right. And it is super interesting. And it does, by the way, have to do with hair regrowth. incredibly rare everywhere on earth except one small village in the Dominican Republic called Salinas. In Salinas, one out of 90 boys are born with this condition.
Before any of this was understood, one would have been justified in saying that in Salinas, one out of 90 girls born turn into boys at around 12 years of age, which is what people used to think.
Before any of this was understood, one would have been justified in saying that in Salinas, one out of 90 girls born turn into boys at around 12 years of age, which is what people used to think.
Before any of this was understood, one would have been justified in saying that in Salinas, one out of 90 girls born turn into boys at around 12 years of age, which is what people used to think.
As we know, at conception, a person destined to be a girl has a set of X chromosomes, while a person destined to become a boy has an X and a Y. Then, at around eight weeks after conception, the sex hormones kick in. If you're genetically male, the Y chromosome instructs your gonads to become testicles and sends testosterone to something called the tubercle.
As we know, at conception, a person destined to be a girl has a set of X chromosomes, while a person destined to become a boy has an X and a Y. Then, at around eight weeks after conception, the sex hormones kick in. If you're genetically male, the Y chromosome instructs your gonads to become testicles and sends testosterone to something called the tubercle.
As we know, at conception, a person destined to be a girl has a set of X chromosomes, while a person destined to become a boy has an X and a Y. Then, at around eight weeks after conception, the sex hormones kick in. If you're genetically male, the Y chromosome instructs your gonads to become testicles and sends testosterone to something called the tubercle.
And the testosterone is converted into... DHT. Ah, yes, DHT. I'm starting to see the connection here. And the DHT turns the tubercle into a penis. And Guevedo says the reason they don't have what we would recognize as a penis when they are born is because they are deficient in an enzyme, which we mentioned earlier, called 5-alpha reductase, which converts testosterone into DHT.
And the testosterone is converted into... DHT. Ah, yes, DHT. I'm starting to see the connection here. And the DHT turns the tubercle into a penis. And Guevedo says the reason they don't have what we would recognize as a penis when they are born is because they are deficient in an enzyme, which we mentioned earlier, called 5-alpha reductase, which converts testosterone into DHT.
And the testosterone is converted into... DHT. Ah, yes, DHT. I'm starting to see the connection here. And the DHT turns the tubercle into a penis. And Guevedo says the reason they don't have what we would recognize as a penis when they are born is because they are deficient in an enzyme, which we mentioned earlier, called 5-alpha reductase, which converts testosterone into DHT.
But at puberty, when genetic males get a second blast of testosterone, they finish growing the penis. This is why people believed that these girls were growing a penis at 12.
But at puberty, when genetic males get a second blast of testosterone, they finish growing the penis. This is why people believed that these girls were growing a penis at 12.
But at puberty, when genetic males get a second blast of testosterone, they finish growing the penis. This is why people believed that these girls were growing a penis at 12.
You're right. It does open up a whole host of new questions, and I'm sure we could do a whole episode here. So I'll just hit you with this little fact that I thought was so interesting. Despite being raised as girls, most Cueva Doses grow up to be heterosexual males. So much for the people who think you can turn someone gay or turn someone straight. Sorry, gay conversion advocates.
You're right. It does open up a whole host of new questions, and I'm sure we could do a whole episode here. So I'll just hit you with this little fact that I thought was so interesting. Despite being raised as girls, most Cueva Doses grow up to be heterosexual males. So much for the people who think you can turn someone gay or turn someone straight. Sorry, gay conversion advocates.
You're right. It does open up a whole host of new questions, and I'm sure we could do a whole episode here. So I'll just hit you with this little fact that I thought was so interesting. Despite being raised as girls, most Cueva Doses grow up to be heterosexual males. So much for the people who think you can turn someone gay or turn someone straight. Sorry, gay conversion advocates.
Yes, right now. It's because Guavidoses had smaller prostates due to their genetic disorder. Scientists used what they learned about Guavidoses to help people with enlarged prostates. It was in studying Guavidoses that scientists were able to develop Finasteride.
Yes, right now. It's because Guavidoses had smaller prostates due to their genetic disorder. Scientists used what they learned about Guavidoses to help people with enlarged prostates. It was in studying Guavidoses that scientists were able to develop Finasteride.
Yes, right now. It's because Guavidoses had smaller prostates due to their genetic disorder. Scientists used what they learned about Guavidoses to help people with enlarged prostates. It was in studying Guavidoses that scientists were able to develop Finasteride.