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Nick Lane

👤 Person
795 total appearances

Appearances Over Time

Podcast Appearances

Dwarkesh Podcast
Nick Lane – Life as we know it is chemically inevitable

having me here.

Dwarkesh Podcast
Nick Lane – Life as we know it is chemically inevitable

This is fun.

Dwarkesh Podcast
Nick Lane – Life as we know it is chemically inevitable

I love talking about this kind of thing.

Dwarkesh Podcast
Nick Lane – Life as we know it is chemically inevitable

So eukaryotes, what's a eukaryote?

Dwarkesh Podcast
Nick Lane – Life as we know it is chemically inevitable

It's basically the cells that make us up, but also make up plants and make up things like amoeba, fungi, algae.

Dwarkesh Podcast
Nick Lane – Life as we know it is chemically inevitable

So basically everything that's large and complex that you can see is composed of this one cell type called the eukaryotic cell.

Dwarkesh Podcast
Nick Lane – Life as we know it is chemically inevitable

And we have a nucleus where all the DNA is, where all the genes are, and then all those kind of

Dwarkesh Podcast
Nick Lane – Life as we know it is chemically inevitable

machinery cell membranes and things.

Dwarkesh Podcast
Nick Lane – Life as we know it is chemically inevitable

There's just basically a lot of kit in these cells.

Dwarkesh Podcast
Nick Lane – Life as we know it is chemically inevitable

And the weirdness is, if you look inside a plant cell or a fungal cell, it looks exactly the same under an electron microscope as one of our cells.

Dwarkesh Podcast
Nick Lane – Life as we know it is chemically inevitable

But they have a completely different lifestyle.

Dwarkesh Podcast
Nick Lane – Life as we know it is chemically inevitable

So why would they have all the same kit if they evolved to be a single-celled alga living in an ocean doing photosynthesis?

Dwarkesh Podcast
Nick Lane – Life as we know it is chemically inevitable

It's still got the same kit that our cells have.

Dwarkesh Podcast
Nick Lane – Life as we know it is chemically inevitable

So we know that because they share all of these things, they arose once.

Dwarkesh Podcast
Nick Lane – Life as we know it is chemically inevitable

in the whole history of life on Earth, there could have been multiple origins, but there's no evidence for that.

Dwarkesh Podcast
Nick Lane – Life as we know it is chemically inevitable

If there was, it disappeared without trace.

Dwarkesh Podcast
Nick Lane – Life as we know it is chemically inevitable

So we've got this kind of singularity, which happened about 2 billion years ago, about 2 billion years into the history of life on Earth.

Dwarkesh Podcast
Nick Lane – Life as we know it is chemically inevitable

Then this thing happens once that gives rise to all complex life on Earth.

Dwarkesh Podcast
Nick Lane – Life as we know it is chemically inevitable

And the one thing which I guess you could conclude from that is bacteria and archaea

Dwarkesh Podcast
Nick Lane – Life as we know it is chemically inevitable

In terms of their genetic repertoire, they're actually, they've got a lot more genes, a lot more versatility than eukaryotes do.

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