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Nick Lane

๐Ÿ‘ค Person
795 total appearances

Appearances Over Time

Podcast Appearances

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

You can't kind of evolve into something more complex.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

To some extent, you can, but basically you're always going to get the same.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

In the same environment, we'll always give you the same thing.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

Soon as you start introducing random bits of RNA into this, then you've got what you'd call evolvability, which is to say you can begin to resist the environment.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

You can begin to do things which are not just dictated by the environment.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

You can evolve and change and leave events in the end and do other things.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

So as soon as you've got genes, you've got the potential to do almost anything.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

If you've got naked bits of RNA, what tends to happen is they're selected for their replication speed.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

They just go on making copies of themselves.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

They don't become more complex.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

They don't start encoding metabolism.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

They just go on copying themselves and it's a dead end.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

if you're trapping them inside growing protocells, then effectively they're sharing the same fate.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

And if some of them are capable of making that protocell grow faster, then they will get more copies of themselves because they're inside this protocell.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

The protocell is growing faster.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

It makes a copy of itself and it's still associated.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

So you've got actually selection as we know it in cells today, where the replicator are the genes, but the system which is being reproduced is the cell.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

I'm going to unpack that a little bit.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

So what have mitochondria got to do with sex?

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

So what they have to do with sex is effectively the female sex.