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Nick Lane

๐Ÿ‘ค Person
795 total appearances

Appearances Over Time

Podcast Appearances

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

She worked on these kind of questions.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

And she saw the growth rate as a common denominator.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

The Y chromosome is basically saying grow fast.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

Why would he grow fast?

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

Well, in part, you can grow fast.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

You don't have any constraints on trashing your own mitochondria.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

Because you're not passing them on.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

So you can grow fast and be an advantage to growing fast.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

If you're a male, you're going to get the resources.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

You grow faster.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

If you're a female, you don't want to grow so fast because you need to effectively cordon off your germline to preserve the oocytes for the next generation.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

And until you've done that, you don't want to trash your mitochondria.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

So you've got a delay phase before you can start growing fast.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

Ursula Mitvoeck argued that that was exactly the case.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

We don't know for a fact that that's true, but it's quite common that females live longer than males, not just in humans, but in Drosophila as well, they do, usually.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

Well, there are, and it has disappeared altogether in some species.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

And usually what you retain is one gene, which causes a different rate of growth.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

So really, the Y chromosome, yes, it's degenerate.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

It's lost most of its genes.

Dwarkesh Podcast
Nick Lane โ€“ Life as we know it is chemically inevitable

The thing about Mueller's ratchet, which is the degradation of things when you don't have sex or you don't have any recombination, there's two factors that influence it.