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Paul Glaziou

👤 Person
47 total appearances

Appearances Over Time

Podcast Appearances

Talk Evidence
Talk Evidence covid-19 update - covid ethics, waste and a minimum RCT size

A lot of groups are trying to coordinate things, but because there's no central body to coordinate research, people have often been putting out feelers to try and work out where that's going on.

Talk Evidence
Talk Evidence covid-19 update - covid ethics, waste and a minimum RCT size

And it's been tricky.

Talk Evidence
Talk Evidence covid-19 update - covid ethics, waste and a minimum RCT size

So WHO has been trying to do that for the vaccine trials, which are probably the most important trials we're going to be doing.

Talk Evidence
Talk Evidence covid-19 update - covid ethics, waste and a minimum RCT size

And they have suggested there'd be a coordination of the international effort so that there was effectively one control arm with all of the different vaccine arms.

Talk Evidence
Talk Evidence covid-19 update - covid ethics, waste and a minimum RCT size

I think that sort of coordination would be a very good idea.

Talk Evidence
Talk Evidence covid-19 update - covid ethics, waste and a minimum RCT size

And it's clearly a role that WHO could potentially play across the board.

Talk Evidence
Talk Evidence covid-19 update - covid ethics, waste and a minimum RCT size

But of course, they've got a lot of other things on their plate as well.

Talk Evidence
Talk Evidence covid-19 update - covid ethics, waste and a minimum RCT size

And so it could be the research funders instead who get together.

Talk Evidence
Talk Evidence covid-19 update - covid ethics, waste and a minimum RCT size

One of the things that we've found very striking in looking through clinicaltrials.gov and other registries of what research is going on is there has been a fantastic number of trials of treatments started up and underway.

Talk Evidence
Talk Evidence covid-19 update - covid ethics, waste and a minimum RCT size

The trials of vaccines are going along at breathtaking speed.

Talk Evidence
Talk Evidence covid-19 update - covid ethics, waste and a minimum RCT size

So we've now got half a dozen that are now in there, at least phase one human type trials going on, which is just astonishing.

Talk Evidence
Talk Evidence covid-19 update - covid ethics, waste and a minimum RCT size

But

Talk Evidence
Talk Evidence covid-19 update - covid ethics, waste and a minimum RCT size

What we've failed to do from looking at the trials registries is to do the trials on improving what we're doing at the moment that's working.

Talk Evidence
Talk Evidence covid-19 update - covid ethics, waste and a minimum RCT size

We don't have many things that are effective.

Talk Evidence
Talk Evidence covid-19 update - covid ethics, waste and a minimum RCT size

We've got basically different types of social distancing, for example, and the hand hygiene and perhaps masks.

Talk Evidence
Talk Evidence covid-19 update - covid ethics, waste and a minimum RCT size

That's still a great uncertainty.

Talk Evidence
Talk Evidence covid-19 update - covid ethics, waste and a minimum RCT size

There are some other things that we could be looking at, like

Talk Evidence
Talk Evidence covid-19 update - covid ethics, waste and a minimum RCT size

ventilation within rooms or even some interesting stuff about copper surfacing, for example.

Talk Evidence
Talk Evidence covid-19 update - covid ethics, waste and a minimum RCT size

You might have seen the report that showed that coronavirus will live for several days on hard surfaces like steel or plastic.

Talk Evidence
Talk Evidence covid-19 update - covid ethics, waste and a minimum RCT size

But if you copper coat the surface, it will only live for minutes or hours at best.