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Peter Attia

๐Ÿ‘ค Speaker
See mentions of this person in podcasts
2609 total appearances

Appearances Over Time

Podcast Appearances

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

Or maybe, you know, at the end of high school, I was 200 pounds, which is, I'll probably never get back into those genes again.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

But by the end of my freshman year of college, I was 220.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

That was kind of a good weight for me.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

And then it's just kind of gone downhill from there.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

You had this orthopedic.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

There's the story of how you got to be 300 pounds.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

Yeah, most people can figure out.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

220 is probably my goal weight.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

And that's what I should be targeting.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

So you made a great point, which is how do we reconcile the following?

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

So caloric restriction as an intervention, as a zero protective intervention is the oldest one in the book.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

I'm not really aware of an intervention where a non-genetic intervention that has from a longer standing perspective produced a more consistent outcome in terms of laboratory animals, where you restrict them to calories and they're going to live longer.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

So again, to my knowledge, there are only two interventions that have extended life across all four models of organisms from yeast, worms, flies, and mammals, rodents.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

And that is caloric restriction and rapamycin.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

And they have something in common, which is they both result in the downregulation of mTOR.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

So we also know that an amino acid you just mentioned a moment ago called leucine is the single most important of all the amino acids at turning up mTOR.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

So how can we reconcile the idea that protein seems to be good for you

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

But mTOR going down seems to be good for you, at least in another way.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

Well, for one... I'm being very facetious because you know I know the answer to this question.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

They're not under threat.