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Prof. Pierre Zalloua

๐Ÿ‘ค Speaker
427 total appearances

Appearances Over Time

Podcast Appearances

The Ancients
The First Arabians

I mean, we're trying so hard.

The Ancients
The First Arabians

And actually, from that visit that you and I had, colleagues there, they're trying to actually get some good quality DNA out of the samples that they have.

The Ancients
The First Arabians

But still to date, we have not been able to get that.

The Ancients
The First Arabians

So ancient DNA, so every single cell of our body or the skeleton supposedly has DNA.

The Ancients
The First Arabians

But with time, cells get very porous.

The Ancients
The First Arabians

And then if there's no collagen to keep the bones together, you lose a lot of the skeleton of the cell itself and DNA is no longer there.

The Ancients
The First Arabians

So you need some form of skeleton to fix the DNA to it.

The Ancients
The First Arabians

So we basically use certain parts of the skeleton, namely the teeth and the molar, precisely because if you can actually drill within the molar part, you can actually extract DNA and you hope that there is DNA inside.

The Ancients
The First Arabians

So that's one part that we can get DNA from.

The Ancients
The First Arabians

But most recently, and I say recently, over the last five years or so, we discovered that the petrous bone, which is, yes, which is below the ear,

The Ancients
The First Arabians

right at the end of the mandible, it's very thick.

The Ancients
The First Arabians

It's actually one of the thickest, if not the thickest bone in the body.

The Ancients
The First Arabians

Because it's thick, it actually can withstand a lot of heat and a lot of climatic changes, et cetera.

The Ancients
The First Arabians

And we can actually extract DNA from it.

The Ancients
The First Arabians

And that's what most scientists have been successful with is extracting DNA from petrous bones.

The Ancients
The First Arabians

And actually, this was a major shift in the way we extract DNA.

The Ancients
The First Arabians

So basically, you grind that bone.

The Ancients
The First Arabians

And then when you grind that bone, you basically, you dissolve all the material into an aqueous phase and then liquid phase.

The Ancients
The First Arabians

And then you get the DNA out and you analyze the DNA.