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Prof. Pierre Zalloua

πŸ‘€ Speaker
427 total appearances

Appearances Over Time

Podcast Appearances

The Ancients
The First Arabians

We will.

282.89 View full episode β†’
The Ancients
The First Arabians

I mean, we're trying so hard.

283.751 View full episode β†’
The Ancients
The First Arabians

And actually, from that visit that you and I had, colleagues there, they're trying to actually get some good quality DNA out of the samples that they have.

285.254 View full episode β†’
The Ancients
The First Arabians

But still to date, we have not been able to get that.

295.592 View full episode β†’
The Ancients
The First Arabians

So ancient DNA, so every single cell of our body or the skeleton supposedly has DNA.

307.578 View full episode β†’
The Ancients
The First Arabians

But with time, cells get very porous.

316.83 View full episode β†’
The Ancients
The First Arabians

And then if there's no collagen to keep the bones together, you lose a lot of the skeleton of the cell itself and DNA is no longer there.

320.034 View full episode β†’
The Ancients
The First Arabians

So you need some form of skeleton to fix the DNA to it.

330.648 View full episode β†’
The Ancients
The First Arabians

So we basically use certain parts of the skeleton, namely the teeth and the molar, precisely because if you can actually drill within the molar part, you can actually extract DNA and you hope that there is DNA inside.

335.354 View full episode β†’
The Ancients
The First Arabians

So that's one part that we can get DNA from.

353.218 View full episode β†’
The Ancients
The First Arabians

But most recently, and I say recently, over the last five years or so, we discovered that the petrous bone, which is, yes, which is below the ear,

355.581 View full episode β†’
The Ancients
The First Arabians

right at the end of the mandible, it's very thick.

364.43 View full episode β†’
The Ancients
The First Arabians

It's actually one of the thickest, if not the thickest bone in the body.

368.337 View full episode β†’
The Ancients
The First Arabians

Because it's thick, it actually can withstand a lot of heat and a lot of climatic changes, et cetera.

372.746 View full episode β†’
The Ancients
The First Arabians

And we can actually extract DNA from it.

379.639 View full episode β†’
The Ancients
The First Arabians

And that's what most scientists have been successful with is extracting DNA from petrous bones.

382.081 View full episode β†’
The Ancients
The First Arabians

And actually, this was a major shift in the way we extract DNA.

388.531 View full episode β†’
The Ancients
The First Arabians

So basically, you grind that bone.

392.577 View full episode β†’
The Ancients
The First Arabians

And then when you grind that bone, you basically, you dissolve all the material into an aqueous phase and then liquid phase.

395.361 View full episode β†’
The Ancients
The First Arabians

And then you get the DNA out and you analyze the DNA.

402.953 View full episode β†’