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Professor Matthew Kiernan

๐Ÿ‘ค Speaker
877 total appearances

Appearances Over Time

Podcast Appearances

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

It's a new test.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

Yes.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

Relatively.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

No, it's a new test.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

And apolipoprotein is one of... It turns out there's lots of different types.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

There's lots of different forms.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

You know, one, two, three, four, five.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

Four is the critical one, but...

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

These apolipoproteins help other processes, other nutrients come in and out of cells.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

But the issue about apolipoprotein E4 is that it is involved in the removal of amyloid and plaques.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

So if you have higher numbers or manifestations of that, the breakdown of amyloid in the brain is not as good.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

So that makes you more prone to Alzheimer's disease.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

So amyloid and tau are proteins in the brain that are linked to a specific form of dementia, Alzheimer's disease.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

Is that right?

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

That's the most common.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

And that's the sort of the center of memory function in our human brain.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

But it doesn't have to be there.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

It could also be some people start losing their vision.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

So it could be in the occipital region.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

It can be lots of different parts of the brain.