Professor Matthew Kiernan
๐ค SpeakerAppearances Over Time
Podcast Appearances
But that's not available at the moment.
The other thing is when you start knocking out certain genes, you don't know what the downstream effects of that are.
The knock-on effect is.
Yeah, exactly.
Because it might be good for something else.
Yeah, and it might be a catastrophe.
There were trials, for instance, in Parkinson's disease, putting in stem cells into the brain and it all sounded great.
It was looking good.
But then the stem cells started to overgrow and cause cancer.
And so people were coming in with overgrowth and cancerous cells in the brain.
So it was a catastrophe.
So you've got to be able to understand.
And that's really why human trials are so critical.
So a model is only as good as the disease it models.
But I think we have to get more and more into patients and patients with neurological conditions.
Of course, we need basic science and discovery, but we've got to focus on the human.
What is this anxiety about memory?
Well, I think once we start focusing on it, we all become anxious.
Like hearing your story there, I was feeling a bit anxious.
So that's something natural.