Professor Tim Spector

I think for people who really need them, they're an incredible drug.

The only problem is you can't really come off them.

So they're pretty much for life.

My first worry is that a lot of people take them without supervision and they are not told to change their diet.

I'd love people to go take the drugs.

The hunger signal gets switched off.

They can then be mindful about their food.

They could do something like, you know, have the Zoe app or some other educational program to change their food habits forever in that window of opportunity.

And that, I think, is where we should be doing.

And that's been completely ignored at the moment.

Virtually nobody's getting that lifestyle advice as well as the drug.

And so they're failing, they're going back and they're, you know, yo-yoing and they're getting the worst of the world.

The other slight worry we need to keep an eye on is the risk.

long-term effects on the brain.

So far, the data suggests that it does reduce your chances of getting dementia, even beyond reversing diabetes.

So it looks like it's brain protective, probably because it might have anti-inflammatory effects.

It reduces things like gambling and addictions.

So we don't really know how it does that.

But if it takes away some of those drives, those basic drives to say, I like to take risks, you know, I like to take drugs, I like to smoke, I like to gamble on horses.

Is it in some way changing you as a person long term in that you might be less good as an entrepreneur, for example?