Rhonda Patrick, Ph.D.

But if you're looking over the course of, like, you know, several years and you have better mitochondria, more healthy mitochondria on top of, like,

you know, improved glucose regulation to the glute transporters and all that, you're probably also going to just see a healthier metabolic profile, right?

I mean, that's

For sure.

Right.

And we don't really have any good biomarkers for mitochondrial health.

It hasn't been translated to the clinic yet.

It's something that researchers can do.

In fact, I'm talking about some of the studies that Marty Gabala cited on the podcast previously.

For volume-matched exercise, high-intensity interval training is better at increasing mitochondrial biogenesis than moderate-intensity exercise.

Again, it has to do with that

stronger stimulus causing the adaptation when you're forcing your muscles to work so hard that they can't produce all the energy they need from just using their mitochondria alone.

It forces them to also use just glucose without mitochondria.

Your muscle's like, dude, I need more mitochondria.

This isn't working, right?

So that's an adaptation that's happening and it makes sense.

And so I know a lot of people for, I've at least gotten a lot of questions from people talking about, but I thought zone two training was the best for mitochondria.

And

You know, it depends on what we're talking about here.

If we're talking about mitochondrial biogenesis, you know, great.