Rhonda Patrick, Ph.D.

Because when you're working hard, your muscles are producing lactate.

And that lactate essentially signals to your muscle to increase these GLUT4 transporters.

These are the transporters that are responsible for bringing glucose out of your circulation, pulling it into the muscle.

And so lactate's actually what is responsible for that signaling effect.

to increase the GLUT4 number or translocation to the cell surface, muscle cell surface.

And so what happens is that you're basically with the more intense or the more vigorous intensity of the activity, the more glucose you're going to bring in because you're having more of those transporters there.

And the transporters actually last around for a while.

So there's a lasting effect.

It's not like they just, they're there when you're working out and then they go back.

No, they stay active for quite a while, right?

Bringing more glucose in.

And so it's unbelievable to actually think about how beneficial vigorous intensity activity is if you're thinking about a 10 times efficient.

I've seen, and I know that there's been a couple of studies showing that vigorous intensity activity

You can do like 15 minutes of vigorous intensity activity, and that's equivalent to like 45 minutes of moderate intensity in terms of glucose regulation.

I would say there's even other studies out there showing like a 1 to 5 ratio as well.

But this study itself, if we're talking about outcome, not just biomarker data, we're talking about outcomes.

We're talking about new diagnosis of diabetes.

It suggested a 1 to 10 ratio, almost.

It was 9.4, but almost 1 to 10.

So I really do think that this confirms that, you know, obviously we've looked at a lot of biomarker data with these randomized controlled trials.