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Rhonda Patrick

๐Ÿ‘ค Speaker
See mentions of this person in podcasts
3873 total appearances

Appearances Over Time

Podcast Appearances

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

But ultimately, I think, you know, and I've talked to a variety of experts, Brad Schoenfeld, Sue Phillips, they agree that really, if you're someone that's overweight or obese, you shouldn't be calculating it based on your actual weight because your protein requirements are way too high.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

It's more like your target weight.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

If you empirically could measure your lean body mass, that would be better.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

But yeah, I just wanted to point that out.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

Yeah.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

And it's like, oh gosh, where do we start?

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

Because let's ignore the worm and the fly and all that because who cares?

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

I mean, even the rodents, it's a stretch.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

You know what else turns on mTOR?

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

Exercise.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

Physical activity, mechanical force turns it on in our muscle.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

And we know exercise is like one of the best things that we can do for our health.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

I think here, I think for simplicity, the best way to think about this is that you want mTOR active in your skeletal muscle.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

You want it active in your skeletal muscle.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

You don't necessarily always want it active systemically, but if you are exercising, if you're moving around,

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

and you're taking in your protein, it's going to your muscle.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

We know that for a fact.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

I talked about anabolic resistance and how exercise can counter that.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

Well, it's increasing the leucine transporter, the expression of leucine transporter.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

It's causing leucine and other branch chain amino acids to go up into skeletal muscle.