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Rhonda Patrick

๐Ÿ‘ค Speaker
See mentions of this person in podcasts
3873 total appearances

Appearances Over Time

Podcast Appearances

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

Because if you look at a lot of the protective effects of rapamycin, I'm like, this is what exercise does.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

And exercise does it better.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

So I'm just not convinced that someone who's already bought into like how important exercise is, both cardiovascular and weight training is.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

Yeah.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

Well, that's interesting.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

I've also seen data with rapamycin given to people that were undergoing resistance training and it like blunted, obviously, some of the muscle protein synthesis as would be expected.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

I don't remember the dose of rapamycin.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

It wasn't super, super high.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

But to me, that was like enough to be like, well...

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

Well, to get back to the mTOR story, I think that recent study, I don't know, it was in the last couple of years it came out.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

It was the animal study where they gave mice 25 grams of protein and mTOR was activated in macrophages.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

And it was like this whole story was pieced together about... 25 grams of protein?

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

Sorry, maybe it was the equivalent dose.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

The human equivalent dose was 25 grams, yeah.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

But it was essentially like arguing that atherosclerosis was being caused by protein.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

I'm like, are you kidding me?

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

Like, for one, we know atherosclerosis, the bigger story there is not protein.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

But again, it comes down to this whole activating mTOR in systemic circulation versus the leucine going to the muscle because you're physically active.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

And keep in mind, those transporters, the leucine transporters, they're pretty sensitive for quite a while.

The Peter Attia Drive
#369 โ€’ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

I mean, you're talking about at least 24 hours, maybe even longer, but definitely 24 hours.