Rick Doblin

And people have felt that sometimes, and I think it's very much the case, that you're tired after MDMA, that people talk about a serotonin depletion. And so when you take 5-HTP, that can be helpful. But when we started with the FDA, they said, all this information that you've got from before from underground use or from before when it was still legal doesn't matter to us.

And people have felt that sometimes, and I think it's very much the case, that you're tired after MDMA, that people talk about a serotonin depletion. And so when you take 5-HTP, that can be helpful. But when we started with the FDA, they said, all this information that you've got from before from underground use or from before when it was still legal doesn't matter to us.

Really, everything has to be done under direct supervision of FDA proof studies. And they said, don't assume that you're going to have problems and you're going to use MDMA plus 5-HTP or something. Just start with the MDMA, see what problems you get, and then you can start. So the way we think about MDMA therapy is that it's really not a one-day thing, it's a two-day.

Really, everything has to be done under direct supervision of FDA proof studies. And they said, don't assume that you're going to have problems and you're going to use MDMA plus 5-HTP or something. Just start with the MDMA, see what problems you get, and then you can start. So the way we think about MDMA therapy is that it's really not a one-day thing, it's a two-day.

Really, everything has to be done under direct supervision of FDA proof studies. And they said, don't assume that you're going to have problems and you're going to use MDMA plus 5-HTP or something. Just start with the MDMA, see what problems you get, and then you can start. So the way we think about MDMA therapy is that it's really not a one-day thing, it's a two-day.

in the sense that the second day is for rest. It's for having no obligations, no appointments, and the therapists come back and do more integrative therapy the next day. And also, we do the therapy during the day. It starts at 10 in the morning. It's an eight-hour session, so often people can get sleep that night.

in the sense that the second day is for rest. It's for having no obligations, no appointments, and the therapists come back and do more integrative therapy the next day. And also, we do the therapy during the day. It starts at 10 in the morning. It's an eight-hour session, so often people can get sleep that night.

in the sense that the second day is for rest. It's for having no obligations, no appointments, and the therapists come back and do more integrative therapy the next day. And also, we do the therapy during the day. It starts at 10 in the morning. It's an eight-hour session, so often people can get sleep that night.

And we don't see more low mood or more tiredness in the people that get MDMA than in the people that got therapy without MDMA. So we were never felt that the need to introduce 5-HTP. We didn't have evidence of symptoms that required this. But I think it's because we talk about it as a two-day experience.

And we don't see more low mood or more tiredness in the people that get MDMA than in the people that got therapy without MDMA. So we were never felt that the need to introduce 5-HTP. We didn't have evidence of symptoms that required this. But I think it's because we talk about it as a two-day experience.

And we don't see more low mood or more tiredness in the people that get MDMA than in the people that got therapy without MDMA. So we were never felt that the need to introduce 5-HTP. We didn't have evidence of symptoms that required this. But I think it's because we talk about it as a two-day experience.

The other part is that when people take MDMA at raves or parties and things like that, often they're drinking. They do it at night. They don't get full sleep. The next day, they don't just take the day off. Often they go into – Right, and they're exhausted. And they're exhausted. Yeah, makes sense.

The other part is that when people take MDMA at raves or parties and things like that, often they're drinking. They do it at night. They don't get full sleep. The next day, they don't just take the day off. Often they go into – Right, and they're exhausted. And they're exhausted. Yeah, makes sense.

The other part is that when people take MDMA at raves or parties and things like that, often they're drinking. They do it at night. They don't get full sleep. The next day, they don't just take the day off. Often they go into – Right, and they're exhausted. And they're exhausted. Yeah, makes sense.

And so I think that this concept that we've developed is this really thinking about it as a two-day experience where there is this low energy, but it can be productive. in terms of trying to work on the issues that came up during the MDMA experience or the PTSD or depression or whatever it is.

And so I think that this concept that we've developed is this really thinking about it as a two-day experience where there is this low energy, but it can be productive. in terms of trying to work on the issues that came up during the MDMA experience or the PTSD or depression or whatever it is.

And so I think that this concept that we've developed is this really thinking about it as a two-day experience where there is this low energy, but it can be productive. in terms of trying to work on the issues that came up during the MDMA experience or the PTSD or depression or whatever it is.

Now, there's a project at a place called Sunstone, which is a therapy center outside in Rockville, Maryland. And they've worked with cancer patients who are anxious about dying. And they have brought in their partners to the therapy, and both of them get MDMA as well. So these are all under FDA-approved studies.

Now, there's a project at a place called Sunstone, which is a therapy center outside in Rockville, Maryland. And they've worked with cancer patients who are anxious about dying. And they have brought in their partners to the therapy, and both of them get MDMA as well. So these are all under FDA-approved studies.

Now, there's a project at a place called Sunstone, which is a therapy center outside in Rockville, Maryland. And they've worked with cancer patients who are anxious about dying. And they have brought in their partners to the therapy, and both of them get MDMA as well. So these are all under FDA-approved studies.