Rick Doblin

So the analogy is you're taking off in an airplane and there's all this turbulence at the beginning and then you get above the clouds and it's smooth sailing. So it's kind of like that with MDMA. But the part that we discovered that was very surprising was we did a study with veterans, firefighters, and police officers.

And one group got 30 milligrams, one group got 75 milligrams, and one group got 125 milligrams. And in that particular study, when you—it was about 26 people— when you randomize, it doesn't mean that everything's equal. It just means it's random. So the people that had 125 milligrams with PTSD had more depression than the people that had 75 milligrams.

And one group got 30 milligrams, one group got 75 milligrams, and one group got 125 milligrams. And in that particular study, when you—it was about 26 people— when you randomize, it doesn't mean that everything's equal. It just means it's random. So the people that had 125 milligrams with PTSD had more depression than the people that had 75 milligrams.

And one group got 30 milligrams, one group got 75 milligrams, and one group got 125 milligrams. And in that particular study, when you—it was about 26 people— when you randomize, it doesn't mean that everything's equal. It just means it's random. So the people that had 125 milligrams with PTSD had more depression than the people that had 75 milligrams.

But the 75 milligram dose group did better than the 125. Interesting. Just slightly better. So what it meant was that the dose that's therapeutically effective was lower than we thought. Can

But the 75 milligram dose group did better than the 125. Interesting. Just slightly better. So what it meant was that the dose that's therapeutically effective was lower than we thought. Can

But the 75 milligram dose group did better than the 125. Interesting. Just slightly better. So what it meant was that the dose that's therapeutically effective was lower than we thought. Can

Yeah, please.

Yeah, please.

Yeah, please.

Yes, yes. Okay.

Yes, yes. Okay.

Yes, yes. Okay.

Well, we evaluate everybody's PTSD symptoms and their depression symptoms. And so just by the randomization, it turned out that those people that were higher on depression ended up more of them in the 125. Just randomly?

Well, we evaluate everybody's PTSD symptoms and their depression symptoms. And so just by the randomization, it turned out that those people that were higher on depression ended up more of them in the 125. Just randomly?

Well, we evaluate everybody's PTSD symptoms and their depression symptoms. And so just by the randomization, it turned out that those people that were higher on depression ended up more of them in the 125. Just randomly?

Yeah, because when you randomize again, it doesn't mean that you're making things equal.

Yeah, because when you randomize again, it doesn't mean that you're making things equal.

Yeah, because when you randomize again, it doesn't mean that you're making things equal.

So it was just a chance. Just turned out that way. Turned out that way. How many people were in this group? 26 people were in the entire study. Okay.