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Ryan Knudson

๐Ÿ‘ค Speaker
See mentions of this person in podcasts
2865 total appearances

Appearances Over Time

Podcast Appearances

The Journal.
Fertility Inc.: The Embryo Editing Dinner

Why are people concerned about this technology?

The Journal.
Fertility Inc.: The Embryo Editing Dinner

When you edit an embryo, it changes that person's DNA.

The Journal.
Fertility Inc.: The Embryo Editing Dinner

But tweaks made at the embryo stage can also be heritable, meaning scientists aren't just messing around with one person's genetic code, but potentially their kid's too, and their kid's kids.

The Journal.
Fertility Inc.: The Embryo Editing Dinner

So if any of those edits goes wrong, the impact could be huge.

The Journal.
Fertility Inc.: The Embryo Editing Dinner

But there's another concern, and it's less to do with the science of embryo editing and more to do with what it could mean for society.

The Journal.
Fertility Inc.: The Embryo Editing Dinner

Many boosters of embryo editing talk about it as a way to eliminate debilitating genetic diseases, to prevent human suffering before it even begins.

The Journal.
Fertility Inc.: The Embryo Editing Dinner

But critics, like the supporters of that moratorium, worry that once the technology is out of the bag, people won't stop at just curing diseases.

The Journal.
Fertility Inc.: The Embryo Editing Dinner

Hmm, right, there could be some group of people that are enhanced and therefore smarter, better, stronger, faster, and then they could pass that on to their own offspring, and then suddenly you have like a new class of human.

The Journal.
Fertility Inc.: The Embryo Editing Dinner

Embryo editing, with the intention of bringing a baby to term, is illegal in many countries around the world, including the U.S.,

The Journal.
Fertility Inc.: The Embryo Editing Dinner

Today, the Food and Drug Administration can't even consider applications for clinical trials if they involve creating a pregnancy with an edited embryo.

The Journal.
Fertility Inc.: The Embryo Editing Dinner

But that hasn't stopped powerful people in Silicon Valley from wanting to do just that, including Coinbase CEO Brian Armstrong.

The Journal.
Fertility Inc.: The Embryo Editing Dinner

Armstrong has made it clear he's interested in edits that would prevent diseases.

The Journal.
Fertility Inc.: The Embryo Editing Dinner

But he's also expressed interest in the exact thing those scientists were worried about, designing better humans.

The Journal.
Fertility Inc.: The Embryo Editing Dinner

It's what some in Silicon Valley refer to as enhancements.

The Journal.
Fertility Inc.: The Embryo Editing Dinner

Yeah, we'll cure some diseases and we'll also get, you know, some taller, more handsome people with full heads of hair.

The Journal.
Fertility Inc.: The Embryo Editing Dinner

First of all, if you haven't seen Gattaca, highly recommend.

The Journal.
Fertility Inc.: The Embryo Editing Dinner

The movie stars Ethan Hawke, Uma Thurman, and Jude Law.

The Journal.
Fertility Inc.: The Embryo Editing Dinner

And it's set in a future where embryos are carefully screened and selected to produce the best babies.

The Journal.
Fertility Inc.: The Embryo Editing Dinner

We didn't want, I mean, diseases, yes, but... Armstrong seems to have taken some inspiration from the movie.

The Journal.
Fertility Inc.: The Embryo Editing Dinner

In a tweet last April, Armstrong wrote about his vision for an IVF clinic of the future, powered by a combination of technologies that he described as, quote, the Gattaca stack.