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Sam Fazeli

👤 Speaker
634 total appearances

Appearances Over Time

Podcast Appearances

Vanguards of Health Care by Bloomberg Intelligence
Fosun Pharma’s Drive Beyond China

Now, in terms of the drug that I forgot, it's Fresenio, of course.

Vanguards of Health Care by Bloomberg Intelligence
Fosun Pharma’s Drive Beyond China

So we have Fresenio, Ibrans, and Kiskali in the CDK4-6 inhibitors.

Vanguards of Health Care by Bloomberg Intelligence
Fosun Pharma’s Drive Beyond China

And Fresenio is Lily's, Kiskali is Novartis, and Ibrans is Pfizer.

Vanguards of Health Care by Bloomberg Intelligence
Fosun Pharma’s Drive Beyond China

Yes, sorry, I should...

Vanguards of Health Care by Bloomberg Intelligence
Fosun Pharma’s Drive Beyond China

Well, you know, I'm in England.

Vanguards of Health Care by Bloomberg Intelligence
Fosun Pharma’s Drive Beyond China

So I come up with my own pronunciation for stuff.

Vanguards of Health Care by Bloomberg Intelligence
Fosun Pharma’s Drive Beyond China

Well, and they've been becoming very good at it, even better recently, making it major tongue twisters.

Vanguards of Health Care by Bloomberg Intelligence
Fosun Pharma’s Drive Beyond China

So let's touch on very quickly on HLX43.

Vanguards of Health Care by Bloomberg Intelligence
Fosun Pharma’s Drive Beyond China

We saw some data at WCLC for this agent, which is an antibody drug conjugate targeting PD-L1.

Vanguards of Health Care by Bloomberg Intelligence
Fosun Pharma’s Drive Beyond China

I am slightly biased towards drugs that use PD-L1 for a targeting agent.

Vanguards of Health Care by Bloomberg Intelligence
Fosun Pharma’s Drive Beyond China

methodology which of course from it you get kind of a double whammy you get potentially tumor targeting but of course PD-L1 is not just tumor cell expressed and you also get inhibition of PD-L1

Vanguards of Health Care by Bloomberg Intelligence
Fosun Pharma’s Drive Beyond China

So you get a double whammy in there, whereas if you just use a PD-1, in fact, you clearly risk killing the T-cells.

Vanguards of Health Care by Bloomberg Intelligence
Fosun Pharma’s Drive Beyond China

Talk to us a little bit about this agent and what your hopes are.

Vanguards of Health Care by Bloomberg Intelligence
Fosun Pharma’s Drive Beyond China

Here you're in a slightly different setup, recurrent metastatic esophageal carcinoma, squamous carcinoma, and actually advanced non-small cell lung cancer.

Vanguards of Health Care by Bloomberg Intelligence
Fosun Pharma’s Drive Beyond China

So talk to us a little bit about where this is going and where your hopes are.

Vanguards of Health Care by Bloomberg Intelligence
Fosun Pharma’s Drive Beyond China

Well, we're certainly watching it.