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Sara Ashley O'Brien

👤 Speaker
80 total appearances

Appearances Over Time

Podcast Appearances

WSJ What’s News
Why Everyone Is Talking About Peptides

It's the sort of promise that people always want, like you want to not get the sun exposure, but you want to look tan and glowing.

WSJ What’s News
Why Everyone Is Talking About Peptides

Peptides are short chains of amino acids.

WSJ What’s News
Why Everyone Is Talking About Peptides

They act as signaling messengers that help your body regulate different functions.

WSJ What’s News
Why Everyone Is Talking About Peptides

They might work in one part of the body and they signal things to other parts of the body as well.

WSJ What’s News
Why Everyone Is Talking About Peptides

Insulin is a peptide.

WSJ What’s News
Why Everyone Is Talking About Peptides

So insulin helps your body turn food into energy and manages your blood sugar levels.

WSJ What’s News
Why Everyone Is Talking About Peptides

Now, if the body doesn't make insulin, that's where a synthetic insulin injection would come into play.

WSJ What’s News
Why Everyone Is Talking About Peptides

GLP-1 is the next sort of obvious one.

WSJ What’s News
Why Everyone Is Talking About Peptides

Now, GLP-1 is a peptide that exists in their body.

WSJ What’s News
Why Everyone Is Talking About Peptides

It's also the basis for pharmaceutical drugs like Ozempic.

WSJ What’s News
Why Everyone Is Talking About Peptides

And what it does, it sort of triggers the feelings in your body of being full, and it shuts down your hunger signals.

WSJ What’s News
Why Everyone Is Talking About Peptides

A synthetic GLP-1 drug like Ozempic is engineered to basically last a lot longer than the natural GLP-1 does that exists in people's bodies today.

WSJ What’s News
Why Everyone Is Talking About Peptides

So that's why people tend to eat less and they tend to stay full for longer when they are taking Ozempic or one of the GLP-1 drugs.

WSJ What’s News
Why Everyone Is Talking About Peptides

The term is very broad, as you've kind of alluded to.

WSJ What’s News
Why Everyone Is Talking About Peptides

People are injecting peptides that they say are for everything from like muscle recovery to hair growth to making their skin glow, a lot of physical but also aesthetic benefits.

WSJ What’s News
Why Everyone Is Talking About Peptides

But the ones that people are often talking about on places like TikTok and Instagram that they're injecting at home are

WSJ What’s News
Why Everyone Is Talking About Peptides

unapproved drugs.

WSJ What’s News
Why Everyone Is Talking About Peptides

So a lot of them are based on anecdotal evidence, but they have not gone through the same lengthy approvals that a drug like Ozempic has to go through, like the clinical trials and all of that to prove the safety effectiveness and the manufacturing process for the drug.

WSJ What’s News
Why Everyone Is Talking About Peptides

In 2023, under the Biden-era FDA, a number of these peptides were banned.

WSJ What’s News
Why Everyone Is Talking About Peptides

Compounding pharmacies were no longer able to legally make these peptides, and that sort of created this gray market online.

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