Saranya Wyles, M.D., Ph.D.

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416 appearances 1 recordings 1 series first heard Jan 2026 last heard 11 Jan

Saranya Wyles, M.D., Ph.D.’s voice in public audio — every appearance, attributed to the second.

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The mindbodygreen Podcast · 632: The science of skin aging & how to slow it down | Saranya Wyles, M.D., Ph.D. · 11 Jan 2026 podcast

A lot of this is based on studies of skin disease.

So a lot of times we look at psoriasis as an example.

So psoriasis is a condition where patients have haphazard turnover of keratinocytes, which is that top layer of

of skin and the epidermis, these cells kind of regulate how psoriasis plays a role on skin and it's an immune mediated disease.

So what we found is there was a study that looked at a 16 week Mediterranean diet intervention.

So by optimizing diet to have more Mediterranean rich foods,

47% of these patients actually had a better PASI score.

So PASI score correlates with 75% improvement in psoriasis severity.

So about nearly 50% improved by being on just a Mediterranean diet.

And this goes on and on.

We've also seen similar studies related to acne risk and looking at patients' glycemic load and glucose intake and how that correlates with patients that have different episodes of acne and acne flare.

So really eating, you know, when it comes down to it, I think...

We're still learning about what are the gut-rich microbiomes that will translate to the skin microbiome and how that connectivity and which foods are the key players.

But right now we're kind of just highlighting, you know, eating colorful plants, Mediterranean olive oil, nuts, seeds, fatty fish, those types of simple prescriptive habits.

Absolutely.

So movement is so key and movement is so important.

Looking at aerobic exercise, resistance training, it really allows the skin to perspire.

And that's a really important ability for the skin to get rid of toxins.

So you want to sweat.

You want to be able to actively create an environment so that the body and the skin is excreting toxins.

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