Founder's Story
The Testosterone Myth That’s Costing Men Years of Their Lives | Ep 299 with Shalin Shah CEO of Marius Pharmaceuticals
That's not true.
Founder's Story
The Testosterone Myth That’s Costing Men Years of Their Lives | Ep 299 with Shalin Shah CEO of Marius Pharmaceuticals
The largest randomized trial in history around testosterone was done specifically to look at testosterone and heart attack risk, and it found there was no correlation.
Founder's Story
The Testosterone Myth That’s Costing Men Years of Their Lives | Ep 299 with Shalin Shah CEO of Marius Pharmaceuticals
So that has been done and put to bed.
Founder's Story
The Testosterone Myth That’s Costing Men Years of Their Lives | Ep 299 with Shalin Shah CEO of Marius Pharmaceuticals
That study actually came out, it was the Traverse study, came out in 2023.
Founder's Story
The Testosterone Myth That’s Costing Men Years of Their Lives | Ep 299 with Shalin Shah CEO of Marius Pharmaceuticals
So it's already two and a half years old there, but it's still making its way into general
Founder's Story
The Testosterone Myth That’s Costing Men Years of Their Lives | Ep 299 with Shalin Shah CEO of Marius Pharmaceuticals
general public, but frankly, patients and providers are still just finding out about this, right?
Founder's Story
The Testosterone Myth That’s Costing Men Years of Their Lives | Ep 299 with Shalin Shah CEO of Marius Pharmaceuticals
That's one.
Founder's Story
The Testosterone Myth That’s Costing Men Years of Their Lives | Ep 299 with Shalin Shah CEO of Marius Pharmaceuticals
Second is that testosterone causes prostate cancer.
Founder's Story
The Testosterone Myth That’s Costing Men Years of Their Lives | Ep 299 with Shalin Shah CEO of Marius Pharmaceuticals
Also, a myth that's been put to bed, not just by the study that I just mentioned, but numerous other studies that have been done historically, and all the way back to the original paper that
Founder's Story
The Testosterone Myth That’s Costing Men Years of Their Lives | Ep 299 with Shalin Shah CEO of Marius Pharmaceuticals
proposed this, basically.
Founder's Story
The Testosterone Myth That’s Costing Men Years of Their Lives | Ep 299 with Shalin Shah CEO of Marius Pharmaceuticals
It was a study in the 1940s with three patients.
Founder's Story
The Testosterone Myth That’s Costing Men Years of Their Lives | Ep 299 with Shalin Shah CEO of Marius Pharmaceuticals
One was female, so you had two guys, and one guy got prostate cancer, right?
Founder's Story
The Testosterone Myth That’s Costing Men Years of Their Lives | Ep 299 with Shalin Shah CEO of Marius Pharmaceuticals
He was an older gentleman, which they all have that chance anyway.
Founder's Story
The Testosterone Myth That’s Costing Men Years of Their Lives | Ep 299 with Shalin Shah CEO of Marius Pharmaceuticals
So that's another big one.
Founder's Story
The Testosterone Myth That’s Costing Men Years of Their Lives | Ep 299 with Shalin Shah CEO of Marius Pharmaceuticals
But I think the third...
Founder's Story
The Testosterone Myth That’s Costing Men Years of Their Lives | Ep 299 with Shalin Shah CEO of Marius Pharmaceuticals
General misconception is, and I call it a misunderstanding, is just how important this is.
Founder's Story
The Testosterone Myth That’s Costing Men Years of Their Lives | Ep 299 with Shalin Shah CEO of Marius Pharmaceuticals
Again, I mentioned there's an androgen receptor on every organ in your body.
Founder's Story
The Testosterone Myth That’s Costing Men Years of Their Lives | Ep 299 with Shalin Shah CEO of Marius Pharmaceuticals
So it plays a role in your cognitive health, in your cardiovascular health, your bone health, your muscle health, your fat metabolism, even all the way down to your mitochondrial, right, which is your cellular level.
Founder's Story
The Testosterone Myth That’s Costing Men Years of Their Lives | Ep 299 with Shalin Shah CEO of Marius Pharmaceuticals
There's a role for testosterone in those processes.
Founder's Story
The Testosterone Myth That’s Costing Men Years of Their Lives | Ep 299 with Shalin Shah CEO of Marius Pharmaceuticals
So I think we've discounted how important this thing is and how helpful it can be for our general health.