Sir John Bell

the strategies in 2017 for Teresa about what we would do as a nation to support life sciences.

And it was interesting because I brought a group of pharma companies together to say, look, this is for you guys.

So tell us what you want done.

We had a series of meetings and what became clear is that they were really interested in where healthcare was going to end up in the next 20 years.

And they said, you guys should try and get ahead of that wave.

And so we agreed that one of the domains that really hadn't been explored properly was the whole concept of prevention, early diagnosis and prevention, which they were smart enough to realize that the kind of current paradigm of treating everybody in the last six months of life

You know, you can make money doing that, there's no doubt, but it doesn't really fix the problem.

And so they said, look, we would love it if you created a cohort from the age of 18 that was big enough that we could actually track the trajectories of people with these diseases, identify them at a pre-symptomatic stage, intervene with preventative therapies, diagnose diseases earlier, and see if we could fundamentally change the whole approach to public health.

Anyway, we went back and did those numbers because, of course, it's a much wider age group.

A lot of people don't get it all sick, but we thought if we collected 5 million people, we would probably have enough.

That's 10% of the UK population, adult population.

So anyway, amazingly, the government said, off you go.

We then had COVID, which, as you know, kept you and I busy for a few years before we could get back to it.

But then we got at it and

We hired a great guy by the name of Riley Valley who had done a bit of this in the UAE and he came across and we set up a population health recruitment structure which was community-based and we rapidly started to recruit people.

We've now got 2.9 million people registered, 2.3 million people consented, and we've got blood in the bank and all the necessary data, including questionnaire data, for 1.5 million people growing up.

So we will get to 5 million, and it's amazing.

No, I know you're a passionate believer in this.

And we need to do a lot of things.

So we need to work out, you know, what's the trial protocol for primary prevention?