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SPEAKER_04

👤 Person
2416 total appearances

Appearances Over Time

Podcast Appearances

The Joe Rogan Experience
#2372 - Garry Nolan

But basic research was sort of the height, and there was a push against anybody trying to commercialize.

The Joe Rogan Experience
#2372 - Garry Nolan

So when I started as an assistant professor, so I started as a grad student.

The Joe Rogan Experience
#2372 - Garry Nolan

I went to MIT to work with this guy, David Baltimore, who won the Nobel for reverse transcriptase research.

The Joe Rogan Experience
#2372 - Garry Nolan

And then I wanted to come straight back to Stanford because I already felt that it was a positive environment for commercialization.

The Joe Rogan Experience
#2372 - Garry Nolan

My former boss's mentors, Len and Lee Herzberg, had two of the biggest patents at Stanford.

The Joe Rogan Experience
#2372 - Garry Nolan

They had the fluorescence-activated cell sorter and then what are called humanized antibodies, which brought in hundreds and hundreds of millions of dollars to Stanford.

The Joe Rogan Experience
#2372 - Garry Nolan

And actually, they gave personally most of their own money away.

The Joe Rogan Experience
#2372 - Garry Nolan

They kept enough to survive, but then they gave most of the money away and they ran their own lab off of a lot of that money.

The Joe Rogan Experience
#2372 - Garry Nolan

So I had learned from them about how to still do basic research but commercialize on the side.

The Joe Rogan Experience
#2372 - Garry Nolan

And so I wanted to bring that back, but the department that I came into, the Department of Pharmacology at the time,

The Joe Rogan Experience
#2372 - Garry Nolan

I was warned by many professors, don't commercialize that.

The Joe Rogan Experience
#2372 - Garry Nolan

And I ignored them and I went and started a company that went public on NASDAQ.

The Joe Rogan Experience
#2372 - Garry Nolan

And many of those same professors came back to me years later and sitting in my office asking me how to start a company.

The Joe Rogan Experience
#2372 - Garry Nolan

It just was instinctual because I couldn't see the NIH funding what I wanted to do.

The Joe Rogan Experience
#2372 - Garry Nolan

So I had developed a way, this will sound scary, but I developed a way to use retroviruses and make libraries of retroviruses to reverse the process of evolution in a way that rather than viruses hurting the cell, I set it up so that viruses would help the cell.

The Joe Rogan Experience
#2372 - Garry Nolan

And once they helped the cell, I would figure out what they did.

The Joe Rogan Experience
#2372 - Garry Nolan

And so we sold hundreds of millions of dollars of targets that way using retroviral libraries to basically find targets and use some of the benefits of viruses but to our advantage.

The Joe Rogan Experience
#2372 - Garry Nolan

Well, I had developed in David's lab, along with this guy, Warren Pear, a means.

The Joe Rogan Experience
#2372 - Garry Nolan

It's called the 293T retroviral producer system.

The Joe Rogan Experience
#2372 - Garry Nolan

It was a way to make large numbers of these viruses very quickly.