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Theo Jaffee

πŸ‘€ Speaker
359 total appearances

Appearances Over Time

Podcast Appearances

The a16z Show
The Shift in Global Drug Development

And then they go, okay, let's audit your entire history here.

The a16z Show
The Shift in Global Drug Development

And so you're just shortening the approval loops, right?

The a16z Show
The Shift in Global Drug Development

And you're just taking out a bunch of kind of review periods.

The a16z Show
The Shift in Global Drug Development

I mean, this is the nature of kind of any, if anyone watching right now, if you've ever worked with, I mean, if you've ever tried to like do some minor renovations in your house and it required some approval from a local,

The a16z Show
The Shift in Global Drug Development

It's not a criticism necessarily.

The a16z Show
The Shift in Global Drug Development

It's just like the nature of administrative review is you submit something and then an actual person usually has to sit down and look at what you've submitted and they have to check it against a bunch of standards.

The a16z Show
The Shift in Global Drug Development

And that itself is like good social technology because it drives a bunch of good outcomes.

The a16z Show
The Shift in Global Drug Development

But the nature of that process is it takes a long time.

The a16z Show
The Shift in Global Drug Development

If you do something wrong or you don't put the right data in or you label something incorrectly, they have to come back to you and you just go back to the bottom of the pile.

The a16z Show
The Shift in Global Drug Development

And it sounds like you're talking about basically they've streamlined the process in such a way

The a16z Show
The Shift in Global Drug Development

that the actual administrative review process is much faster, but at the same time, they've kind of tried to keep the policy goals of the administrative review process intact.

The a16z Show
The Shift in Global Drug Development

So the outcome is at the same standard, but the process is much improved.

The a16z Show
The Shift in Global Drug Development

Is that right?

The a16z Show
The Shift in Global Drug Development

Oh, interesting.

The a16z Show
The Shift in Global Drug Development

And the way, I mean, it's contextualized again, it's like 600 days.

The a16z Show
The Shift in Global Drug Development

I mean, if you, the thing that drives, the thing that drives this is if you are a pharmaceutical company, you've invested a bunch of different, you know, a bunch of money in developing a drug, a target, 600 days might just like make that financially non-viable, right?

The a16z Show
The Shift in Global Drug Development

So it's just raising the walls to try and compete with a cheap generic.

The a16z Show
The Shift in Global Drug Development

And so like, I mean, again, to contextualize it, it's like, if you look at the price of the amount of the percentage of GDP spent on healthcare, it just kind of goes up.

The a16z Show
The Shift in Global Drug Development

If you look at US drug prices compared to the rest of the world, they're quite a lot higher.

The a16z Show
The Shift in Global Drug Development

There are lots of different reasons for that.