Tsvi B. T. (TSVIBT)

End quote.

Seek significantly enhancing.

The effect is greatly attenuated compared to germline genetics.

In adulthood, learning windows have been passed by.

Many genes are no longer active.

Damage that accumulates has already been accumulated.

Many cells don't receive the edits.

This adds up to an optimistic ceiling somewhere around plus 2 or plus 3 SDS.

Method.

Make a baby from a cell that has a genome that has many IQ-positive genetic variants.

End quote.

Subtasks.

Know what genome would produce geniuses.

This is already solved well enough.

Because there are already polygenic scores for IQ that explain greater than 12% of the observed variance in IQ, link in text 10 SDS of raw selection power would translate into trait selection power at a rate greater than square root, 1 9th, equals 1 3rd, giving greater than 3.3 SDS of IQ trait selection power, that is plus 50 IQ points.

Make a cell with such a genome.

This is probably not that hard, via CRISPR editing stem cells, via iterated meiotic selection, or via chromosome selection.

My math and simulation show that several methods would achieve strong intelligence amplification.

If induced meiosis into culturable cells is developed, IMS can provide greater than 10 SDS of raw selection power given very roughly $10.05 and a few months.

Know what epigenomic state, in sperm, egg as eye goat, leads to healthy development.