Yo-El Ju

So it's hard to beat placebo in insomnia.

So, you know, the bar is extremely high.

But overall, when it comes to melatonin, it does help for people who have delayed sleep phase or, you know, if they're night owls, particularly if taken a couple hours before bedtime.

For people who want to take it for trouble sleeping, I think it's reasonable to try because it has a generally benign side effect profile.

But if it doesn't help, then people should just, you know, they shouldn't keep taking it with some belief that it'll like build up over time and help them.

It doesn't.

You know, I think if it's going to help, it'll help.

Otherwise, people can throw in the towel.

So magnesium helps sometimes.

I think some of this is related to some insomnia actually being a symptom of restless legs.

And so some people report that their restless legs is better with magnesium.

And so I think it may help in those cases.

I have a lot of patients who take magnesium.

They're not quite sure if it helps, but they still take it.

I think the main potential side effect is it can cause diarrhea or stomach upset.

So if it doesn't hurt them, I say go ahead.

But I have not been, you know, similar to all supplements.

You know, if they worked really great, I think they would make them prescription.

So I don't think any of those, you know, have, you know, randomized effects.

double-blind controlled clinical trials where I've been really impressed that it beats placebo.