Ziva Cooper

But real quick, some botanical and cultural history, shall we?

So according to the University of Sydney's article, The History of Cannabis, the plant cannabis sativa has been used by humans since at least 2800 BCE.

And Indian Hindus, Greeks, Romans, more cultures have relied on it as a remedy for, quote, a vast array of different health problems, including arthritis, depression, menstrual issues, inflammation, pain, lack of appetite, and asthma.

And the word ganja, by the way, I thought that was just a catch-all, but it refers to the female flowers of the plant where most of the cannabinoids hang out.

What about all those floppy leaves?

You ask, well, you can't eat them and become stony.

It's not like catnip.

THC needs heating, and that's called decarboxylation, to convert it from something called THCA, which doesn't do much for you, to just THC, which does a lot for you.

So let's chat with Carolyn again to get more history of humans and hashish.

And so let's get back to how these things are just doing their thing.

What do those receptors normally do or where do we make those cannabinoids in our body?

Those come from like exercise or eating or let's say that you don't live in a place where it's legal or you just don't like getting high.

How do we make those usually?

And according to a 2021 Harvard Health article titled The Endocannabinoid System, Essential and Mysterious, the cannabinoid receptors in our brain, one of them is a CB1 receptor.

They act like it says traffic cops to control the levels and activity of most of the other neurotransmitters.

And that is how they're regulating things.

They're giving immediate feedback.

They're

They're turning up, they're turning down the activity of whichever system needs to be adjusted.

It says whether that's hunger or temperature or alertness.