ZOE Health App: AI, and the Fight Against Ultra-Processed Food

What if the food we eat every day is silently undermining our health, and AI holds the key to reversing it?In this episode of AI at Work, I sit down with Jonathan Wolf, co-founder and CEO of Zoe, to explore the intersection of AI, microbiome science, and the future of personalized nutrition. If Zoe sounds familiar, it’s likely because of their groundbreaking COVID study app or their clinical trial published in Nature Medicine proving Zoe’s approach is more effective than standard dietary advice. But this isn’t just about test kits or health trends.Jonathan shares the origin story behind Zoe, including how a chance meeting with Professor Tim Spector turned a pivot from adtech into a mission-led company focused on improving the health of millions. We explore:How AI is powering Zoe’s free new app launching in the USThe dangers of ultra-processed food and what’s really inside your mealsWhy personalized advice and behavior change, not food tracking or perfection, are key to long-term healthWhat shotgun metagenomics can tell you about your gut and why that mattersThe ethical challenge of combating food industry misinformation at scaleFrom photo-based food recognition to conversational AI that understands your microbiome, Jonathan breaks down how science, data, and product design are working together to make health advice smarter and more accessible.Whether you're a founder thinking about your next pivot or someone just trying to eat better without obsessing over every bite, this conversation offers real insight and practical steps.

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