Artificial Intelligence and Biological Misuse: Differentiating Risks of Language Models and Biological Design Tools

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Recorded05 Dec 2025

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Handlerec:14272462

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This paper proposes two categories of AI models that could have impacts on biosecurity in different ways: large language models (LLMs) and biological design tools (BDTs). Overall, the author suggests that LLMs could lower barriers to biological misuse, while BDTs could expand the capabilities of sophisticated actors to create pandemic pathogens worse than anything seen to date. The paper also provides suggestions for mitigating these risks.Original text:https://arxiv.org/abs/2306.13952Author(s):Jonas B. SandbrinkA podcast by BlueDot Impact.Learn more on the AI Safety Fundamentals website.

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