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AMC Clinical Deep Dive

EP083 - Schizophrenia Medication Change_ Thioridazine to Atypical Antipsychotic

04 Aug 2025

Description

This podcast is based on clinical scenarios from the official AMC Handbook of Clinical Assessment published by the Australian Medical Council. All cases are used solely for study and discussion. We provide personal learning insights and clinical interpretations to support AMC candidates in developing their clinical reasoning skills. The AMC Handbook is the intellectual property of the Australian Medical Council. To access the official material, please visit the AMC website. This episode outlines a clinical scenario involving a 35-year-old woman with chronic schizophrenia whose medication, thioridazine, needs to be changed due to potential life-threatening cardiac side effects, specifically QT interval prolongation. The core purpose is to assess a healthcare professional's ability to communicate effectively with a patient about the necessity of this medication change, explaining the risks of the current treatment, as well as the benefits and potential side effects of newer atypical antipsychotics. It emphasises the importance of a thorough discussion of alternative treatments, including their efficacy and common adverse effects like weight gain and hyperprolactinemia, to ensure informed patient consent and a smooth transition to a new medication.#AMC #OSCE #ClinicalReasoning #MedicalEducation #IMGs #AustralianMedicalCouncil #SchizophreniaTreatment #AntipsychoticMedication #ThioridazineRisks #AtypicalAntipsychotics #MentalHealthManagement #MedicationChange #ChronicSchizophrenia #QTcProlongation #PatientCare #HealthcareInsights

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