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Anaphylaxis UK: Let's Talk About Allergies

Understanding Penicillin Allergies: What Every GP Should Know

20 Feb 2025

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In this short episode, we revisit a conversation between our Chief Executive Simon and GP & Allergy Specialist Dr. Helen Evans Howells, as they delve into the complexities of penicillin allergies and the process of delabelling. Despite many patients believing they’re allergic to penicillin, research shows that only about 1% truly are. This mislabelling can lead to unnecessarily longer hospital stays and a heightened risk of complications, underscoring the importance of accurate diagnosis.Dr. Helen explains how GPs can better assess a reported penicillin allergy by exploring the severity and history of reactions. This approach not only helps ensure patients receive the most appropriate care but also minimises the potential complications associated with an incorrect allergy label.Dr. Helen Evans-Howells, GP and allergy specialist, chairs the Anaphylaxis UK Clinical & Scientific Panel. She runs Dr Helen Allergy, a private clinic for adults and children in Bournemouth and Dorchester, offering virtual consultations and advice. Follow her for allergy and eczema support: drhelenallergy.For the studies referenced in the episode, visit:Wilcock, M., & Powell, N. (2021). Challenges of delabelling penicillin allergy. Drug and Therapeutics Bulletin, 59(11). https://doi.org/10.1136/dtb.2021.000019Ferner, R., & McGettigan, P. (2020). The patient who reports a drug allergy. The BMJ, 368. https://doi.org/10.1136/bmj.l6791

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