Antibuddies

Monolog 28 - Archives of a cell

19 Mar 2026

Contributed by Lukas

In this monolog, Vijay talks about TimeVault, a novel technology that allows capturing and storing mRNA in mammalian cells. Check out our memes...

Monolog 27 - Discovery of NK cells (Part-3)

24 Jan 2026

Contributed by Lukas

In this multipart monolog, Jatin talks about some milestone discoveries related to natural killer cells.

Monolog 26 - Beta cell death paradox in T1D

17 Nov 2025

Contributed by Lukas

Vijay talks about a 2025 publication delineating the role of efferocytosis by pancreatic macrophages in modulating type I diabetes.

Monolog 25 - Skintabodies

30 Oct 2025

Contributed by Lukas

In this monolog, Casey talks about a recently discovered role of Skin in autonomously producing antibodies against microbes.

Monolog 24 - Discovery of NK cells (Part-2)

09 Sep 2025

Contributed by Lukas

In this multipart monolog series, Jatin talks about some milestone discoveries related to natural killer cells.Check out our memes on Facebook (@antib...

Monolog 23 - ILC you in pancreas 2

23 Jun 2025

Contributed by Lukas

In this monolog, Vijay talks about a novel discovery highlighting the role of Innate lymphoid cells in regulation of blood glucose in fasting conditio...

Monolog 22 - ILC you in pancreas

23 Jun 2025

Contributed by Lukas

In this multipart monolog, Vijay talks about a novel discovery highlighting the role of Innate lymphoid cells in regulation of blood glucose in fastin...

Monolog 21 - Discovery of NK cells (Part-1)

14 Apr 2025

Contributed by Lukas

In this multipart monolog, Jatin talks about some milestone discoveries related to natural killer cells. Check out our memes on Facebook (@anti...

Monolog 20 - The Fountain of IL-11 Youth

07 Oct 2024

Contributed by Lukas

In this monolog, Casey discusses a 2024 article about the increase in health and lifespan in mammals after IL-11 inhibition.

Monolog 19 - Term vs Pre-term immune development

23 Sep 2024

Contributed by Lukas

In this monolog, Vijay discusses the difference in immune system development in term and pre-term babies. Sources: https://pubmed.ncbi.nlm.nih.gov/...

Monolog 18 - Interleakin'

27 Aug 2024

Contributed by Lukas

In this monolog, Akshat ponders about the spatiotemporal underpinnings of cytokine concentrations in tissue niches...and how it all appears to functio...

Monolog 17 - CAR-T and TCR-T Cells Face Off!

29 Jul 2024

Contributed by Lukas

In this episode, Akshat outlines the salient features of CAR or TCR-engineered T cells, and deigns to ponder: is one modality just objectively better ...

Monolog 16 - 217 COVID boosters and counting

06 Jul 2024

Contributed by Lukas

In this Monolog, Casey discusses the unique case of a hyper-vaccinated individual in Germany with more than 200 COVID-19 vaccines and how his immunolo...

Monolog 15 - The Liver is Bile-lingual

07 Mar 2024

Contributed by Lukas

In this Monolog, Akshat discusses how the liver "speaks" both immunity and metabolism via bile to control hepatic tumors. Liver X Receptors also make ...

Ep29 - Barrier immunity & the gut

04 Feb 2024

Contributed by Lukas

In the 29th episode of our Immunology 101 series, Ash and Tanu start the new year 2024 with a discussion on Barrier Immunity with a focus on the gut.

Monolog 14 - Sterile inflammation

30 Jan 2024

Contributed by Lukas

In this monologue, Akshat talks about sterile inflammation, or leucocyte activation in the absence of inflammatory responses. These carefully regulate...

Monolog 13 - Sleep tight, don't let the cytokine storm bite

21 Jan 2024

Contributed by Lukas

In this monolog, Casey talks about a 2023 article from the National Institute of Biological Sciences (Beijun, China) about the role of cytokines and i...

Monolog 12 - Gut is the multiverse of neuroimmune activities

16 Jan 2024

Contributed by Lukas

In this monolog, Vijay talks about a 2016 article from Rockefeller University about the complex crosstalk in the gut between the neurons and macrophag...

Ep28 - The Natural killers

23 Dec 2023

Contributed by Lukas

In the 28th episode of our Immunology 101 series, Ash and Jatin talk continue discussion on cytotoxic T cells and transition into their functional cou...

Ep27 - The kiss of death

12 Nov 2023

Contributed by Lukas

In the 27th episode of our Immunology 101 series, Ash and Jatin talk about how cytotoxic T cells deliver the kiss of death to their targets.

Ep26 - Cytotoxic T cells

21 Oct 2023

Contributed by Lukas

In the 26th episode of our Immunology 101 series, Ash and Jatin shift gears from humoral immunity to cellular immunity and discuss cytotoxic T cell ac...

Ep25 - Fc receptors & Antibody isotypes

10 Sep 2023

Contributed by Lukas

In the 25th episode of our Immunology 101 series, Koshika and Jatin discuss Fc receptors and Antibody isotypes and relate them to specific effector fu...

Ep24 - Antibody effector functions

13 Aug 2023

Contributed by Lukas

In the 24th episode of our Immunology 101 series, Ash and Jatin discuss the various effector functions of Antibodies

Ep23 - Somatic hypermutation and Class switching

15 Jul 2023

Contributed by Lukas

In the 23rd episode of our Immunology 101 series, Ash, Koshika, and Jatin discuss the events taking place inside the germinal center - class switching...

Ep22 - B cells in the germinal center

25 Jun 2023

Contributed by Lukas

In the 22nd episode of our Immunology 101 series, Ash, Koshika, and Jatin talk about the events of the germinal centers.

Ep21 - Fate of a B cell

04 Jun 2023

Contributed by Lukas

In the 21st episode of our Immunology 101 series, Ash and Jatin talk about the fate of the B cell after it encounters the antigen and how it travels t...

Bep40 - Non-canonical T cell activation in TDLNs

15 May 2023

Contributed by Lukas

In this Buddisode, we sit down with Dr. Nataliya Prokhnevska to discuss her work on the fate and role of non-cytotoxic CD8+ T cells found in the tumor...

Monolog 11 - Neuro-Pancreas Chat

05 May 2023

Contributed by Lukas

In this monolog, Vijay talks about a recent article describing the communication between the vagus nerve and the pancreas.

Ep20 - B cells are mean

23 Apr 2023

Contributed by Lukas

In the 20th episode of Immunology 101 series, Ash, Koshika, and Jatin shift gears to talk about B cell activation and draw parallels with T cell activ...

Ep19 - Memory T cells

02 Apr 2023

Contributed by Lukas

In the 19th episode of the Immunology 101 series, Ash, Koshika, and Jatin talk continue their conversation about T cell subsets with a focus on memory...

Ep18 - T helper classification and polarization

26 Mar 2023

Contributed by Lukas

In the 18th episode of Immunology 101 series, Ash, Koshika, and Jatin talk about classification of T helper cells and their functions.

Bep39 - How SARS CoV2 aces cytotoxic T cells

15 Mar 2023

Contributed by Lukas

In this Buddisode, we sit down with Drs. Cosima T Baldari & Rino Rappuoli to discuss their work on a unique immune evasion strategy deployed by SARS C...

Ep17 - T cell activation

05 Feb 2023

Contributed by Lukas

In the 17th episode of Immunology 101 series, Natalie and Jatin talk about the T cell activation process and make some very lame jokes.

Monolog 10 - Evolution of Immunity

27 Dec 2022

Contributed by Lukas

In this monolog, Natalie talks about the evolutionary history of the immune system.

Bep38 - Yin and Yang of Tfh

15 Nov 2022

Contributed by Lukas

In this Buddisode, we sit down with Dr. Simon Bélanger from the La Jolla Institute of Immunology (currently at Vir Biotechnology) to discuss his work...

Bep37 - You won't believe what your eosinophils are doing!

23 Oct 2022

Contributed by Lukas

In this Buddisode, we sit down with Dr. Emilie Cosway from the Institute of Immunology and Immunotherapy at the University of Birmingham (UK) to discu...

Bep36 - IL17A and ICI-induced autoimmune thyroiditis

29 Sep 2022

Contributed by Lukas

In this buddisode, we sit down with Dr. Melissa Lechner from the Division of Endocrinology, Diabetes, and Metabolism at the UCLA David Geffen School o...

Bep35 - Aging affects Central Tolerance

07 Sep 2022

Contributed by Lukas

We sit down with Dr. Jessica Lancaster from the Department of Immunology, Mayo clinic to discuss her recent paper about the effect of Aging on Central...

Ep16 - Pathways of the Complement System

09 Aug 2022

Contributed by Lukas

In the 16th episode of Immunology 101 series, Natalie and Jatin talk about an undergrad's worst nightmare 2 months into the immunology course - The co...

Bep34 - A tale of labor, pre-term birth, and IL-22

21 Jun 2022

Contributed by Lukas

We sit down with Dr. Nardhy Gomez-Lopez from the Department of Obstetrics and Gynecology at Wayne State University to discuss her recent paper about t...

Ep15 - Regulation of Innate Immunity

21 Apr 2022

Contributed by Lukas

Natalie and Jatin talk about positive and negative regulation in immune response, how the cells of the innate immunity interact with the adaptive, and...

Ep14 - Innate Immune Cells

31 Mar 2022

Contributed by Lukas

In the 14th episode of Immunology 101 series, Natalie and Jatin talk about the cellular facet of the innate immune system.

Bep33 - Transgenerational trained immunity

21 Mar 2022

Contributed by Lukas

Eugenio and Jatin sit down with Dr. Jorge-Dominguez Andres (Ph.D.) from Radboud University to discuss trained immunity and its transgenerational inher...

Bep32 - 6 shades of NF-kB #2

27 Feb 2022

Contributed by Lukas

We continue our discussion with Dr. Adewunmi Adelaja (M.D., Ph.D.), from the University of California Los Angeles, about NFkB signaling and how signal...

Bep31 - 6 shades of NF-kB #1

18 Feb 2022

Contributed by Lukas

We sit down with Dr. Adewunmi Adelaja (M.D., Ph.D.) from the University of California Los Angeles to discuss NFkB signaling and how signals to differe...

Monolog 9 - Why do we lose smell after COVID19?

08 Feb 2022

Contributed by Lukas

In this monolog, Tanu breaks down a recent study that elucidates the mechanism behind the loss of sense of smell in COVID19 patients.

Monolog 8 - Neuroimmune interactions

29 Jan 2022

Contributed by Lukas

In this monolog, Vijay highlights some of the interactions between the neurons and the immune cells that show an intricately woven neuroimmune network...

Bep30 - Finding the right clone

17 Jan 2022

Contributed by Lukas

We sit down with Dr. Yosuke Kumamoto from Rutgers new jersey medical school to discuss the role of a specific subset of DCs that retain lymphocytes in...

Monolog 7 - Cancer is an immune disease

05 Jan 2022

Contributed by Lukas

In this monolog, Natalie explains how cancer is a disease of the immune system.

Ep13 - Innate immunity and other PRRs

24 Nov 2021

Contributed by Lukas

In the 13th episode of Immunology 101 series, Natalie and Jatin continue talking about PRR signaling.Check out our memes on Facebook (@antibuddies), T...

Ep12 - Innate immunity and TLR signaling

10 Nov 2021

Contributed by Lukas

In the 12th episode of Immunology 101 series, Natalie and Jatin shift gears to talk about Innate immunity with a focus on TLR signaling.Check out our ...

Monolog 6 - TIM3 and Breast cancer

26 Oct 2021

Contributed by Lukas

In this breast cancer awareness month special monolog, Tanu talks about the challenges faced for breast cancer research and finding an effective treat...

Ep11 - B cell development in the spleen

19 Oct 2021

Contributed by Lukas

Immunology 101

Bep29 - Origin of Eukaryotes and the TCA cycle #2

02 Oct 2021

Contributed by Lukas

In the 2nd part of the Origin of Eukaryotes series, Dara and Jatin sit down with Dr. Dylan G Ryan from University of Cambridge (formerly at Trinity Co...

Bep28 - Origin of Eukaryotes and the TCA cycle #1

26 Sep 2021

Contributed by Lukas

In the 1st part of the Origin of Eukaryotes series, Dara and Jatin sit down with Dr. Dylan G Ryan from University of Cambridge (formerly at Trinity Co...

Bep27 - Phase separation in Immune Signaling #2

21 Sep 2021

Contributed by Lukas

In the 2nd part of the phase separation series, Eugenio, Natalie, & Jatin sit down with Xiaolei Su, Qian Xiao, and Ceara McAtee continue their dis...

Bep26 - Phase separation in Immune Signaling #1

14 Sep 2021

Contributed by Lukas

In this Buddisode, Eugenio, Natalie, & Jatin sit down with Xiaolei Su, Qian Xiao, and Ceara McAtee from Yale cancer center at Yale university to d...

Bep25 - Microbe-specific thymocyte development

30 Aug 2021

Contributed by Lukas

In this Buddisode, Dara, Eugenio, Natalie, & Jatin sit down with Daniel from Gretchen Diehl's lab at Memorial Sloan Kettering Cancer Center, NY. T...

Ep10 - B cell development in the bone marrow

15 Aug 2021

Contributed by Lukas

In the 10th episode of Immunology 101 series, Dara, Jatin, and Natalie talk about B cell development in the bone marrow, some key transcription factor...

Bep24 - Type I vs Type II interferons in autoimmunity

01 Aug 2021

Contributed by Lukas

In this Buddisode, Dara & Jatin sit down with Adam Fike from Ziaur Rahman's lab at Penn State University. The discussion entails their 2020 public...

Bep23 - B cells in the Brain

25 Jul 2021

Contributed by Lukas

In this Buddisode, Eugenio, Natalie, and Jatin sit down with Dr. Wei-le Wang who is a posdoc in the lab of Dr. Marco Colonna lab at Washington Univers...

Monolog 5 - Endogenous retroviruses in skin immunity

18 Jul 2021

Contributed by Lukas

In this monolog, Tanu talks about the effect of diet, microbiota, and the endogenous retroviral elements in skin inflammation. Check out our memes on...

Bep22 - Your immune cells determine how fast you age

05 Jul 2021

Contributed by Lukas

In this Buddisode, Eugenio, Natalie, and Jatin sit down with Drs. Rafael Flores and Matthew Yousefzadeh to discuss their recent research that aims to ...

Ep9 - T cell development #2

29 Jun 2021

Contributed by Lukas

In the 9th episode of Immunology 101 series, Dara, Jatin, and Natalie continue talking about T cell development with some details on the molecular lev...

Ep8 - T cell development #1

07 Jun 2021

Contributed by Lukas

In the 8th episode of Immunology 101 series, Dara, Jatin, and Natalie talk about the steps in the development of T cells and how self love is importan...

Bep21 - Neuroinvasive SARS CoV2

11 May 2021

Contributed by Lukas

In this Buddisode, Eugenio, Tanu, and Jatin sit down with Dr. Eric Song from Yale School of Medicine to discuss his recent publication that associates...

Bep20 - Germinal centers in severe COVID19 patients

28 Apr 2021

Contributed by Lukas

In this Buddisode, Eugenio, Dara, and Jatin sit down with Dr. Shiv Pillai from Harvard medical school to discuss about his lab's recent publication ab...

Ep7 - Gene Rearrangement in T cells

12 Apr 2021

Contributed by Lukas

In the 7th episode of Immunology 101 series, Dara, Eugenio, Jatin, and Natalie talk about the discovery of the T cell receptors, the mechanism of VDJ ...

Ep6 - Gene Rearrangement in B cells [Part 2]

28 Mar 2021

Contributed by Lukas

In the 6th episode of Immunology 101 series, Jatin and Natalie talk about the mechanism of VDJ recombination, its epigenetic aspect, and the steps tha...

Bep19 - A new spin to T cell flavors

14 Mar 2021

Contributed by Lukas

In this Buddisode, Eugenio, Natalie, and Jatin sit down with Dr. Evgeny Kiner from Immunai and discuss about his earlier publication about a continuum...

Bep18 - Extrafollicular T cells in SLE

01 Mar 2021

Contributed by Lukas

In this Buddisode, Eugenio, Natalie, and Jatin sit down with Dr. Deepak Rao from Harvard Medical School and discuss about his lab's 2019 publication a...

Monolog 4 - lnc between RNA and CSR.

23 Feb 2021

Contributed by Lukas

In this monolog, Natalie talks about how long non-coding RNAs alter chromosomal conformation to affect class switching in B cells. Check out our meme...

Bep17 - IgM: the key to early neoantigen recognition

15 Feb 2021

Contributed by Lukas

In this buddisode, Eugenio, Natalie, and Jatin sit down with Dr. Claudia Jakubzick from Dartmouth University. They discus Claudia's 2018 publication t...

Bep16 - Decoy exosomes for defense

24 Jan 2021

Contributed by Lukas

In this buddisode, we sit down with Dr. Ken Cadwell from New York University to talk about his recent article about decoy exosomes secreted by epithel...

Ep5 - Gene Rearrangement in B cells [Part 1]

17 Jan 2021

Contributed by Lukas

In the 5th episode of Immunology 101 series, Eugenio, Jatin, Natalie, and Samriti talk about the how such an enormous antibody diversity is generated ...

Bep15 - Mitochondria is the powerhouse of TILs.

08 Dec 2020

Contributed by Lukas

In this buddisode, we sit down with Dr. Yi-ru Yu, a post doctoral researcher at the department of oncology (University of Lausanne, Switzerland) to ta...

Bep14 - Why B cells need co-stimulation?

21 Nov 2020

Contributed by Lukas

In this buddisode, Eugenio, Jatin, and Natalie discuss about the requirement of 2nd signal in B cells.   Check out our memes on Facebook (@antibudd...

Monolog 3 - Why aren't we all autoimmune?

06 Nov 2020

Contributed by Lukas

In this monolog, Jatin talks about some pioneering studies from the early 2000s that unraveled the mystery behind central tolerance.Check out our meme...

Bep13 - Viruses STING!

26 Oct 2020

Contributed by Lukas

In this episode, Eugenio, Jatin, and Natalie discuss about the a the role of STING's Interferon-independent pathways in T cells and macrophages. Chec...

Bep12 - Anxie-T cells

04 Oct 2020

Contributed by Lukas

In this buddisode, Eugenio, Jatin, and Natalie discuss about the a the role T cells in anxiety in murine models. Check out our memes on Facebook (@an...

Bep11 - Colonic Tregs and Mom

20 Sep 2020

Contributed by Lukas

In this buddisode, Eugenio, Jatin, and Natalie discuss about the a unique mode of non-genetic multigenerational inheritance in colonic Tregs. Check o...

Monolog 2 - Don’t blame the butter for what the bread did

27 Aug 2020

Contributed by Lukas

In this monolog, Tanu briefly discusses the recent study from Ang et al. about the effect of ketogenic diet on gut microbiota and Th17 cells. There ar...

Monolog 1 - No mercy for cancer

06 Aug 2020

Contributed by Lukas

In this monolog, Jatin briefly discusses the recent study from Lai et al. about FLT3L-secreting CAR T cells that successfully elicited a polyclonal im...

Bep10 - To IL2 or not to IL2

23 Jul 2020

Contributed by Lukas

In this Buddisode, Antia and Jatin discuss about the unique profiles of T cells that produce and/or respond to Interleukin 2. What determines whether ...

Bep9 - Cancer nano-immunotherapy #2

09 Jun 2020

Contributed by Lukas

In this Buddisode, Antia and Jatin continue to discuss about the recent developments in cancer nano medicine.Check out our memes on Facebook (@antibud...

Bep8 - Cancer nano-immunotherapy #1

30 May 2020

Contributed by Lukas

In this Buddisode, Antia and Jatin discuss about the recent developments in cancer nano medicine. Part 2 will be out soon.Check out our memes on Faceb...

Bep7 - Major love compatibility complex?

07 May 2020

Contributed by Lukas

In this buddisode, Tanu and Jatin discuss about HLA's association with body odor, mate selection, and procreation in humans.   Check out our memes ...

Bep6 - The miracle drug for COVID19?

24 Apr 2020

Contributed by Lukas

In this buddisode, Tanu and Jatin discuss about the WHO mega trial, the breakthrough french study, and discuss some research articles investigating th...

Bep5 - B and T cells have different metabolic requirements

17 Apr 2020

Contributed by Lukas

In this buddisode, Antia and Jatin discuss about a recent study from 2016 that highlights the different metabolic requirements of T and B cells under ...

Bep4 - Dieting improves T memory response

07 Apr 2020

Contributed by Lukas

In this buddisode, Antia and Jatin discuss about a recent study that shows improved secondary immune responses during dietary restriction. Also, Antia...

Bep3 - Immunity against COVID19 / SARS CoV2

30 Mar 2020

Contributed by Lukas

In this buddisode, Tanu and Jatin discuss about a SARS CoV2 patient case study who recovered from non-severe COVID19. Check out our memes on Facebook...

Bep2 - T cell responses against SARS Coronavirus

25 Feb 2020

Contributed by Lukas

In this buddisode, Tanu, a PhD student in virology, tells us about the SARS coronavirus that is related to the CoVID 19 currently in discussion worldw...

Bep1 - Exosomes are cool

08 Dec 2019

Contributed by Lukas

In this buddisode, Dr. Winni Hui talks about her recently published work with exosomes secreted by salmonella infected macrophages. Website: Antibud...

Ep4 - Cells of the immune system

16 Nov 2019

Contributed by Lukas

In the 4th episode of Immunology 101 series, Jatin tells a joke which is not even funny. We also talk about the cells of the immune system and what th...

Ep3 - Genesis of the immune system

18 Oct 2019

Contributed by Lukas

In the 3rd episode of our immunology 101 series, we talk about the birth of the immune system and faith of an immune cell after it has served its func...

Ep2 - Types of Immunity

02 Oct 2019

Contributed by Lukas

In the second episode, Autumn and Jatin talk about the various types of immunity. Check out our memes on Facebook (@antibuddies) and Twitter (@antibu...

Ep1 - The birth of Immunology

02 Oct 2019

Contributed by Lukas

In the first episode of the immunology 101 series, Autumn and Jatin talk about the pioneering scientists whose work gave birth to the field of immunol...