At the Lab
Episodes
On the trail of a cellular cold case
16 Dec 2025
Contributed by Lukas
Join us as we shine light on the mystery of nuclear speckles. Hear about their potential links to cancer and see where the science may take us n...
The worldâs first personalized gene therapy
03 Dec 2025
Contributed by Lukas
The two physician-scientists behind this major biomedical breakthrough sit down with us to discuss their collaboration and whatâs next.Â
Is an AI singularity possible?
19 Nov 2025
Contributed by Lukas
CSHL NeuroAI Scholars Kyle Daruwalla and Christian Pehle donât see so-called âartificial general intelligenceâ anywhere on the horizon. Hereâs...
Pediatric cancers: Rare, relentless, and real
05 Nov 2025
Contributed by Lukas
The science is complex. The stakes are high. And the urgency is immediate.Â
Special edition: Breast Cancer Awareness Month
23 Oct 2025
Contributed by Lukas
CSHL Professor David Spector discusses some of his labâs latest research and the partnership making it possible. Â
S2 Episode 10: An evening out with the brain and body
10 Jun 2025
Contributed by Lukas
Typically, if you hear someone in a bar talking about âconversationsâ between their brain and their body, you might want to call them a cab. Not t...
S2 Episode 9: Catch me if you cancer
03 Jun 2025
Contributed by Lukas
Youâve seen her on FOX and the cover of Newsday. Now, hear about the knowledge gaps that make Claudia Tonelli's discovery so crucial and the noble g...
S2 Episode 8: The human Microprocessor
30 May 2025
Contributed by Lukas
Thereâs a Microprocessor inside you. Actually, there are trillions. Only theyâre not computer processors. Theyâre much smaller and far more comp...
S2 Episode 7: AI evolves
20 May 2025
Contributed by Lukas
Todayâs AI can talk the talk, but it literally canât walk the walk. CSHL neuroscientists discuss the biological brainâs multibillion-year advant...
S2 Episode 6: UTIs in womenâs health
13 May 2025
Contributed by Lukas
âIt started with an accident observation,â says CSHL Associate Professor Camila dos Santos. That observation? A group of lab mice with urinary tra...
S2 Episode 5: The nuclear speckle option
06 May 2025
Contributed by Lukas
Speckles sound innocent enough, like little spots. But donât be fooled. These tiny structures could someday have big implications for cancer care.
S2 Episode 4: Dancing with fire
29 Apr 2025
Contributed by Lukas
It can cause blackouts, memory loss, and hallucinations. Itâs typically diagnosed in people in their 20s and considered more common among women than...
S2 Episode 3: Products of an unseen environment
22 Apr 2025
Contributed by Lukas
Where does autism come from when itâs not genetic? One hypothesis suggests maternal viral infection could be a cause. But how does this work? You ma...
S2 Episode 2: Science for lovers
15 Apr 2025
Contributed by Lukas
You canât spell evolution without l-o-v-e. A tale of passion and curiosity takes us from New York to Australia, France, the U.K., and South America....
S2 Episode 1: A vitamin for prostate cancer
08 Apr 2025
Contributed by Lukas
What if there were a vitamin that could help treat or prevent prostate cancer? We sat down with CSHL Professor Lloyd Trotman to find out about new pr...
Season 1 Research Rewind: AI+
29 Oct 2024
Contributed by Lukas
This seasonâs final Research Rewind brings us from the realm of quantitative biology to neuroscience, genomics, and beyond.
Season 1 Research Rewind: Genetics
22 Oct 2024
Contributed by Lukas
Itâs the code for all life on Earth. This week At the Lab, weâre hacking it with the help of Cold Spring Harbor Laboratoryâs geneticists.
Season 1 Research Rewind: Neuroscience
15 Oct 2024
Contributed by Lukas
What do you think? How do you know? And who are you anyway? We probe each of these questions with the help of Cold Spring Harborâs neuroscientists.
Season 1 Research Rewind: Cancer
08 Oct 2024
Contributed by Lukas
As the first season of our new podcast winds down, weâre revisiting all of our episodes with a focus on CSHLâs cutting-edge cancer research.
Episode 26: The golden grail of genomics
01 Oct 2024
Contributed by Lukas
Step inside EN-TEx, a catalog of more than one million genomic variants, and hear about its potential for the future of science and medicine.
Episode 25: How maize became corn
24 Sep 2024
Contributed by Lukas
Cold Spring Harbor Laboratory solves a plant biology mystery some 4,000 years in the making. The implications may go far beyond vegetables.
Episode 24: Putting the brakes on brain cancer
17 Sep 2024
Contributed by Lukas
CSHL Professor Alea Mills compares the deadly brain cancer glioblastoma to a car with its brakes cut. Her lab works to reattach them.
Episode 23: Cured with CRISPR
10 Sep 2024
Contributed by Lukas
Victoria Gray, the first person ever cured of sickle cell, appeared on a DNA Learning Center panel featuring a clinical scientist from CSHL.
Episode 22: Outmuscling cancer
03 Sep 2024
Contributed by Lukas
After 10 years, CSHL has made a breakthrough in the study of RMS, a rare pediatric cancer. How we got here is a story of innovation and perseverance.
Episode 21: Nature versus nurture
27 Aug 2024
Contributed by Lukas
What makes you, you? CSHL Assistant Professor Gabrielle Pouchelon looks for answers in the brainâs earliest neural connections.
Episode 20: Cleanup on IL-6
20 Aug 2024
Contributed by Lukas
CSHL Professor Bo Li set out to study a tiny group of neurons involved in cancer cachexia. What he found astounded even him.Â
Episode 19: Brain sex
13 Aug 2024
Contributed by Lukas
How are sex differences defined in the brain? CSHL Associate Professor Jessica Tollkuhn delivers a thought-provoking primer on a fascinating topic.
Episode 18: The stress of cancer
06 Aug 2024
Contributed by Lukas
A sobering conversation on a breakthrough discovery with potentially significant implications for cancer patients everywhere.
Episode 17: AI SQUID
30 Jul 2024
Contributed by Lukas
Tune in to this weekâs podcast to hear about the latest artificial intelligence model coming out of Cold Spring Harbor Laboratory.
Episode 16: Bats!
23 Jul 2024
Contributed by Lukas
Shriek if you must. Their remarkable genome might provide new insights into natural links between the immune system, aging, and cancer resistance.
Episode 15: Fruit fliesâ dating lives
16 Jul 2024
Contributed by Lukas
Can AI help us identify the Don Juan of fruit flies? CSHLâs Benjamin Cowley thinks so. Why would we want to do this? Tune in to find out.
Episode 14: Whatâs that smell?
09 Jul 2024
Contributed by Lukas
You might not realize, but that question is central to the human experience. On this weekâs podcast, CSHLâs Saket Navlakha sniffs out answers.
Episode 13: A more sustainable chemistry
02 Jul 2024
Contributed by Lukas
For this weekâs podcast, CSHL Professor John Moses bridges the gap between chemistry and biology in less than three minutes.
Episode 12: Cancer cops
25 Jun 2024
Contributed by Lukas
In this weekâs podcast, CSHL Assistant Professor Semir Beyaz reveals how metastatic breast cancer âcorruptsâ the bodyâs immune system.
Episode 11: AI brainiacs
11 Jun 2024
Contributed by Lukas
What is neuroAI, and how does it help both neuroscientists and computer scientists? In this weekâs podcast, CSHLâs Kyle Daruwalla explains.Â
Episode 10: The time of our lives
04 Jun 2024
Contributed by Lukas
âYou wouldnât start making the fingernails on an arm until you had started to make the arm,â says CSHLâs Christopher Hammell. Howâs that for...
Episode 9: Musical mice
28 May 2024
Contributed by Lukas
We put the âmiceâ in âmaestro,â with singing lessons from Cold Spring Harbor Laboratory neuroscientist Arkarup Banerjee.
Episode 8: Birds of a feather
21 May 2024
Contributed by Lukas
How did some birds get such distinct colors? CSHL Professor Adam Siepel joins us for a journey across evolutionâs âislands of differentiation.â ...
Episode 7: Women in STEM
14 May 2024
Contributed by Lukas
CSHL is no stranger to successful female scientists. Today, we remember the life of Martha Chase, famously known for the Hershey-Chase experiment.Â
Episode 6: Supermoms to the rescue
07 May 2024
Contributed by Lukas
Happy almost Motherâs Day! What drives a supermom to come to the rescue when her child is upset? CSHLâs Stephen Shea shares the biological backsto...
Episode 5: A heart of golf
30 Apr 2024
Contributed by Lukas
A 500-year-old mystery stumbled on by Leonardo da Vinci has been solved using modern clinical data. Meet the CSHL scientist at the heart of it all.
Episode 4: DNA sequencing for all
23 Apr 2024
Contributed by Lukas
CSHL Dolan DNA Learning Centerâs Jason Williams teaches us about a portable DNA sequencer that may turn the tide for genetics education.
Episode 3: Autism Awareness Month
16 Apr 2024
Contributed by Lukas
Itâs Autism Awareness Month! CSHL Professor Ivan Iossofiv shares what researchers know about autism so far and how they plan to uncover its origins....
Episode 2: Molecular puppetry
09 Apr 2024
Contributed by Lukas
CSHL neuroscientist Hiro Furukawa shows us a part of the brain that actually works like a puppet master. What could this mean for mental health?
Episode 1: The tomato of tomorrow
29 Mar 2024
Contributed by Lukas
In the premiere episode of At the Lab, we visit CSHL Professor & HHMI Investigator Zachary Lippman to glimpse the future of food and farming.