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Frameshift: How Caitlin Vander Weele made science communication her business

19 Mar 2026

Contributed by Lukas

Her favorite part of research was talking about it. So she left academia and turned that passion into a successful company.

Signs of aging vary across brain cells

18 Mar 2026

Contributed by Lukas

Senescence presents differently depending on the cell type, toxic trigger and neighboring cells, two new studies find.

Neuroscientists challenge NIH's proposed human-data access policy

17 Mar 2026

Contributed by Lukas

The changes would restrict the sharing of human neuroimaging, transcriptomic and genetic data.

Large-scale neuroimaging datasets often lack information specific to women's health, constraining AI's analysis potential

16 Mar 2026

Contributed by Lukas

Addressing this gap will require collecting widespread data on pregnancy, menopause and other life events women experience—and could bring us closer...

Remembering Annette Dolphin, who helped explain gabapentin's effects

13 Mar 2026

Contributed by Lukas

The “intuitive” neuropharmacologist pushed against the status quo.

Revised statistical bar extracts less-common variants from autism genetics studies

12 Mar 2026

Contributed by Lukas

Adjusting genetic analyses could help plug autism’s heritability gap, according to a new preprint.

This paper changed my life: Talia Lerner reflects on dopamine neuron diversity and the value of simple experiments

11 Mar 2026

Contributed by Lukas

In a 2011 Neuron study, Stephan Lammel and his colleagues showed that dopamine neurons with different projections have different physiological propert...

Hippocampus builds reputation as 'general-purpose statistical learning machine'

10 Mar 2026

Contributed by Lukas

New cross-species findings may help settle a long-standing debate about whether the hippocampus is required for passive learning.

Securing the academic pipeline amid uncertain U.S. funding climate

09 Mar 2026

Contributed by Lukas

Finding creative ways to keep early-career researchers in academia—for example, through part-time roles—can help the field weather the storm.

Shifting neural code powers speech comprehension

05 Mar 2026

Contributed by Lukas

Dynamic coding helps explain how the brain processes multiple features of speech—from the smallest units of sounds to full sentences—simultaneousl...

Astrocytes orchestrate oxytocin's social effects in mice

04 Mar 2026

Contributed by Lukas

The cells amplify oxytocin—and may be responsible for sex differences in social behavior, two preprints find.

Neuro's ark: Spying on the secret sensory world of ticks

03 Mar 2026

Contributed by Lukas

Carola Städele, a self-proclaimed “tick magnet,” studies the arachnids’ sensory neurobiology—in other words, how these tiny parasites zero i...

Lack of reviewers threatens robustness of neuroscience literature

02 Mar 2026

Contributed by Lukas

Simple math suggests that small groups of scientists can significantly bias peer review.

Post-infection immune conflict alters fetal development in some male mice

26 Feb 2026

Contributed by Lukas

The immune-conflict between dam and fetus could help explain sex differences in neurodevelopmental conditions.

Is there a neuroscientist in the House?

25 Feb 2026

Contributed by Lukas

Sam Wang, a neuroscientist running for the U.S. House of Representatives, has been considering American democracy for decades.

Infant visual system categorizes common objects by 2 months of age

24 Feb 2026

Contributed by Lukas

Brain activity patterns in the ventral visual cortex appear to distinguish images across 12 categories, including birds and trees, longitudinal functi...

Frameshift: Raphe Bernier followed his heart out of academia, then made his way back again

20 Feb 2026

Contributed by Lukas

After a clinical research career, an interlude at Apple and four months in early retirement, Raphe Bernier found joy in teaching.

Organoid study reveals shared brain pathways across autism-linked variants

19 Feb 2026

Contributed by Lukas

The genetic variants initially affect brain development in unique ways, but over time they converge on common molecular pathways.

Neuroscience needs single-synapse studies

17 Feb 2026

Contributed by Lukas

Studying individual synapses has the potential to help neuroscientists develop new theories, better understand brain disorders and reevaluate 70 years...

Neuroscience has a species problem

16 Feb 2026

Contributed by Lukas

If our field is serious about building general principles of brain function, cross-species dialogue must become a core organizing principle rather tha...

Oligodendrocytes need mechanical cues to myelinate axons correctly

11 Feb 2026

Contributed by Lukas

Without the mechanosensor TMEM63A, the cells cannot deposit the appropriate amount of insulation, according to a new study.

Aging neurons outsource garbage disposal, clog microglia

10 Feb 2026

Contributed by Lukas

Degradation-resistant proteins pass from neurons to glial cells in a process that may spread protein clumps around the brain, according to a study in ...

From genes to dynamics: Examining brain cell types in action may reveal the logic of brain function

09 Feb 2026

Contributed by Lukas

Defining brain cell types is no longer a matter of classification alone, but of embedding their genetic identities within the dynamical organization o...

Oregon primate research center to negotiate with NIH on possible transition to sanctuary

09 Feb 2026

Contributed by Lukas

The board of directors at Oregon Health & Science University, which runs the primate center, voted unanimously in favor of the move.

Cerebellum responds to language like cortical areas

06 Feb 2026

Contributed by Lukas

One of four language-responsive cerebellar regions may encode meaningful information, much like the cortical language network in the left hemisphere, ...

Neuro's ark: Understanding fast foraging with star-nosed moles

04 Feb 2026

Contributed by Lukas

“MacArthur genius” Kenneth Catania outlined the physiology behind the moles’ stellar foraging skills two decades ago. Next, he wants to better c...

Largest leucovorin-autism trial retracted

03 Feb 2026

Contributed by Lukas

A reanalysis of the data revealed errors and failed to replicate the results.

NIH scraps policy that classified basic research in people as clinical trials

03 Feb 2026

Contributed by Lukas

The policy aimed to increase the transparency of research in humans but created “a bureaucratic nightmare” for basic neuroscientists.

Cell atlas cracks open 'black box' of mammalian spinal cord development

03 Feb 2026

Contributed by Lukas

The atlas details the genetics, birth dates and gene-expression signatures of roughly 150 neuron subtypes in the dorsal horn of the mouse spinal cord....

Betting blind on AI and the scientific mind

02 Feb 2026

Contributed by Lukas

If the struggle to articulate an idea is part of how you come to understand it, then tools that bypass that struggle might degrade your capacity for t...

Viral remnant in chimpanzees silences brain gene humans still use

27 Jan 2026

Contributed by Lukas

The retroviral insert appears to inadvertently switch off a gene involved in brain development.

Why emotion research is stuck-and how to move it forward

26 Jan 2026

Contributed by Lukas

Studying how organisms infer indirect threats and understand changing contexts can establish a common framework that bridges species and levels of ana...

How artificial agents can help us understand social recognition

16 Jan 2026

Contributed by Lukas

Neuroscience is chasing the complexity of social behavior, yet we have not answered the simplest question in the chain: How does a brain know “who i...

Common and rare variants shape distinct genetic architecture of autism in African Americans

15 Jan 2026

Contributed by Lukas

Certain gene variants may have greater weight in determining autism likelihood for some populations, a new study shows.

Bringing African ancestry into cellular neuroscience

14 Jan 2026

Contributed by Lukas

Two independent teams in Africa are developing stem cell lines and organoids from local populations to explore neurodevelopmental and neurodegenerativ...

Computational psychiatry needs systems neuroscience

13 Jan 2026

Contributed by Lukas

Dissecting different parallel processing streams may help us understand the mechanisms underlying psychiatric symptoms, such as delusions, and unite h...

This paper changed my life: John Tuthill reflects on the subjectivity of selfhood

12 Jan 2026

Contributed by Lukas

Wittlinger, Wehner and Wolf’s 2006 “stilts and stumps” Science paper revealed how ants pull off extraordinary feats of navigation using a biolog...

Cracking the neural code for emotional states

08 Jan 2026

Contributed by Lukas

Rather than act as a simple switchboard for innate behaviors, the hypothalamus encodes an animal’s internal state, which influences behavior.

Some facial expressions are less reflexive than previously thought

08 Jan 2026

Contributed by Lukas

A countenance such as a grimace activates many of the same cortical pathways as voluntary facial movements.

Neuro's ark: How goats can model neurodegeneration

06 Jan 2026

Contributed by Lukas

Since debunking an urban legend that headbutting animals don’t damage their brain, Nicole Ackermans has been investigating how the behavior correlat...

The 1,000 neuron challenge

05 Jan 2026

Contributed by Lukas

A competition to design small, efficient neural models might provide new insight into real brains—and perhaps unite disparate modeling efforts.

Remembering Adam Kampff, neuroscience educator and researcher

24 Dec 2025

Contributed by Lukas

Kampff’s do-it-yourself approach inspired a generation of neuroscientists.

'Unprecedented' dorsal root ganglion atlas captures 22 types of human sensory neurons

23 Dec 2025

Contributed by Lukas

The atlas also offers up molecular and cellular targets for new pain therapies.

Not playing around: Why neuroscience needs toy models

22 Dec 2025

Contributed by Lukas

Amid the rise of billion-parameter models, I argue that toy models, with just a few neurons, remain essential—and may be all neuroscience needs.

Psychedelics research in rodents has a behavior problem

19 Dec 2025

Contributed by Lukas

Simple behavioral assays—originally validated as drug-screening tools—fall short in studies that aim to unpack the psychedelic mechanism of action...

New organoid atlas unveils four neurodevelopmental signatures

17 Dec 2025

Contributed by Lukas

The comprehensive resource details data on microcephaly, polymicrogyria, epilepsy and intellectual disability from 352 people.

AI-assisted coding: 10 simple rules to maintain scientific rigor

16 Dec 2025

Contributed by Lukas

These guidelines can help researchers ensure the integrity of their work while accelerating progress on important scientific questions.

How basic neuroscience has paved the path to new drugs

15 Dec 2025

Contributed by Lukas

A growing list of medications—such as zuranolone for postpartum depression, suzetrigine for pain, and the gepants class of migraine medicines—exis...

Waves of calcium activity dictate eye structure in flies

12 Dec 2025

Contributed by Lukas

Synchronized signals in non-neuronal retinal cells draw the tiny compartments of a fruit fly’s compound eye into alignment during pupal development....

What is the future of organoid and assembloid regulation?

10 Dec 2025

Contributed by Lukas

Four experts weigh in on how to establish ethical guardrails for research on the 3D neuron clusters as these models become ever more complex.

Seeing the world as animals do: How to leverage generative AI for ecological neuroscience

08 Dec 2025

Contributed by Lukas

Generative artificial intelligence will offer a new way to see, simulate and hypothesize about how animals experience their worlds. In doing so, it co...

Exclusive: Springer Nature retracts, removes nearly 40 publications that trained neural networks on 'bonkers' dataset

08 Dec 2025

Contributed by Lukas

The dataset contains images of children’s faces downloaded from websites about autism, which sparked concerns at Springer Nature about consent and r...

Psilocybin rewires specific mouse cortical networks in lasting ways

05 Dec 2025

Contributed by Lukas

Neuronal activity induced by the psychedelic drug strengthens inputs from sensory brain areas and weakens cortico-cortical recurrent loops.

Beyond the algorithmic oracle: Rethinking machine learning in behavioral neuroscience

03 Dec 2025

Contributed by Lukas

Machine learning should not be a replacement for human judgment but rather help us embrace the various assumptions and interpretations that shape beha...

This paper changed my life: Nancy Padilla-Coreano on learning the value of population coding

01 Dec 2025

Contributed by Lukas

The 2013 Nature paper by Mattia Rigotti and his colleagues revealed how mixed selectivity neurons—cells that are not selectively tuned to a stimulus...

Noninvasive method lifts curtain on cerebrospinal-fluid dance in human brain

14 Nov 2025

Contributed by Lukas

Cerebrospinal fluid shows brain-region-specific dynamics, a new high-resolution MRI approach reveals.

Aging as adaptation: Learning the brain's recipe for resilience

14 Nov 2025

Contributed by Lukas

Some age-related changes in the brain and in behavior are not solely the result of cognitive decline but rather part of a larger adaptive process.

Perimenopause: An important-and understudied-transition for the brain

12 Nov 2025

Contributed by Lukas

Many well-known perimenopause symptoms arise in the brain, but we still know little about the specific mechanisms at play. More research—in both ani...

Without monkeys, neuroscience has no future

10 Nov 2025

Contributed by Lukas

Research in primate brains has been essential for the development of brain-computer interfaces and artificial neural networks. New funding and policy ...

Our searchable repository of useful research can restore trust in federally funded basic science

05 Nov 2025

Contributed by Lukas

Called U.S. Public Research Benefits, the database showcases the value of basic science in an easy and accessible format.

How neuroscientists are using AI

04 Nov 2025

Contributed by Lukas

Eight researchers explain how they are using large language models to analyze the literature, brainstorm hypotheses and interact with complex datasets...

Neuroscience needs engineers-for more reasons than you think

03 Nov 2025

Contributed by Lukas

Adopting an engineering mindset will help the field focus its research priorities.

Ramping up cortical activity in early life sparks autism-like behaviors in mice

30 Oct 2025

Contributed by Lukas

The findings add fuel to the long-running debate over how an imbalance in excitatory and inhibitory signaling contributes to the autism.

First Pan-African neuroscience journal gets ready to launch

28 Oct 2025

Contributed by Lukas

With lower-than-average article processing fees, and issues dedicated to topics important to the continent, the journal hopes to give African neurosci...

The missing half of the neurodynamical systems theory

27 Oct 2025

Contributed by Lukas

Bifurcations—an underexplored concept in neuroscience—can help explain how small differences in neural circuits give rise to entirely novel functi...

Remembering GABA pioneer Edward Kravitz

24 Oct 2025

Contributed by Lukas

The biochemist, who died last month at age 92, was part of the first neurobiology department in the world and showed that gamma-aminobutyric acid is i...

Protein tug-of-war controls pace of synaptic development, sets human brains apart

23 Oct 2025

Contributed by Lukas

Human-specific duplicates of SRGAP2 prolong cortical development by manipulating SYNGAP, an autism-linked protein that slows synaptic growth.

Neurons tune electron transport chain to survive onslaught of noxious stimuli

22 Oct 2025

Contributed by Lukas

Nociceptors tamp down the production of reactive oxygen species in response to heat, chemical irritants or toxins.

This paper changed my life: Sandra Jurado marvels at the first-ever 3D model of a synaptic vesicle

21 Oct 2025

Contributed by Lukas

In this 2006 Cell paper, Shigeo Takamori and his colleagues showcased the molecular machinery of synaptic vesicles in outstanding detail. Their work t...

Diving in with Nachum Ulanovsky

16 Oct 2025

Contributed by Lukas

With an eye toward realism, the neuroscientist, who has a new study about bats out today, creates microcosms of the natural world to understand animal...

Gene-activity map of developing brain reveals new clues about autism's sex bias

16 Oct 2025

Contributed by Lukas

Boys and girls may be vulnerable to different genetic changes, which could help explain why the condition is more common in boys despite linked varian...

Engrams in amygdala lean on astrocytes to solidify memories

15 Oct 2025

Contributed by Lukas

Disrupting the astrocyte-neuronal dynamic in mice destabilizes their memory of fear conditioning.

Ant olfactory neurons reveal new 'transcriptional shield' mechanism of gene regulation

14 Oct 2025

Contributed by Lukas

A protective screen of spurious transcriptional activity enables each olfactory neuron to express exactly one out of hundreds of olfactory receptors.

New questions around motor neurons and plasticity

10 Oct 2025

Contributed by Lukas

A researcher’s theory hangs muscle degeneration on a broken neural circuit.

One year of FlyWire: How the resource is redefining Drosophila research

07 Oct 2025

Contributed by Lukas

We asked nine neuroscientists how they are using FlyWire data in their labs, how the connectome has transformed the field and what new tools they woul...

Neurons fuel lung tumors that have spread to brain

06 Oct 2025

Contributed by Lukas

Functional synapses between brain cells and cancer cells are key to the metastatic growth, according to new findings from two independent teams.

Why we need basic science to better understand the neurobiology of psychedelics

01 Oct 2025

Contributed by Lukas

Despite the many psychedelics clinical trials underway, there is still much we don’t know about how these drugs work. Preclinical studies represent ...

Reproducibility is a team sport: Lessons from a large-scale collaboration

29 Sep 2025

Contributed by Lukas

Building reproducible systems across labs is possible, even in large-scale neuroscience projects. You just need rigor, collaboration and the willingne...

Local circuit loops within body control fly behavior, new 'embodied' connectome reveals

24 Sep 2025

Contributed by Lukas

The mapping, which traces how the central nervous system interacts with the rest of the body, challenges the idea that behavior control is centralized...

Autism experts question HHS statements on Tylenol, leucovorin

22 Sep 2025

Contributed by Lukas

Concerns include the administration’s reliance on weak, correlational evidence rather than established research.

Beyond Newtonian causation in neuroscience: Embracing complex causality

22 Sep 2025

Contributed by Lukas

The traditional mechanistic framework must give way to a richer understanding of how brains actually generate behavior over time.

This paper changed my life: Dan Goodman on a paper that reignited the field of spiking neural networks

17 Sep 2025

Contributed by Lukas

Friedemann Zenke’s 2019 paper, and its related coding tutorial SpyTorch, made it possible to apply modern machine learning to spiking neural network...

First nerve-net connectome shows how evolutionarily ancient nervous system coordinates movement

16 Sep 2025

Contributed by Lukas

The map of a comb jelly’s aboral nerve net, which helps the animal orient and position itself within the water column, reveals a unique system for s...

Paper by memory institute director garners expression of concern over image integrity

16 Sep 2025

Contributed by Lukas

The notice, posted last week in Nature, follows a recent string of corrections to at least three other articles by Li-Huei Tsai’s lab.

International scientific collaboration is more necessary-yet more challenging-than ever

15 Sep 2025

Contributed by Lukas

These partnerships accelerate neuroscience by enabling researchers to share resources and expertise, as well as generate more relevant and reproducibl...

Sensory gatekeeper drives seizures, autism-like behaviors in mouse model

11 Sep 2025

Contributed by Lukas

The new work, in mice missing the autism-linked gene CNTNAP2, suggests a mechanism to help explain the overlap between epilepsy and autism.

Mitochondria set 'ancient' metabolic thermostat for sleep in flies, separate from circadian rhythms

09 Sep 2025

Contributed by Lukas

During waking hours, a specialized set of sleep neurons in the fly brain accumulates reactive oxygen species, which eventually trigger sleep to clean ...

Building the future of neuroscience at HBCUs

08 Sep 2025

Contributed by Lukas

Black In Neuro is launching a new program to help historically Black colleges and universities advance neuroscience research and education, focusing o...

Emotion research has a communication conundrum

05 Sep 2025

Contributed by Lukas

In 2025, the words we use to describe emotions matter, but their definitions are controversial. Here, I unpack the different positions in this space a...

Autism-linked copy number variants always boost autism likelihood

04 Sep 2025

Contributed by Lukas

By contrast, varied doses of the same genes decrease or increase the odds of five other conditions, with distinct biological consequences, two new pre...

Astrocyte networks span large swaths of brain

03 Sep 2025

Contributed by Lukas

The networks are plastic, connect brain regions that aren’t connected by neurons and may enable long-distance communication between astrocytes, a ne...

From bench to bot: Why AI-powered writing may not deliver on its promise

02 Sep 2025

Contributed by Lukas

Efficiency isn’t everything. The cognitive work of struggling with prose may be a crucial part of what drives scientific progress.

Worms help untangle brain structure/function mystery

29 Aug 2025

Contributed by Lukas

The synaptic connectome of most animals bears little resemblance to functional brain maps, but it can still predict neuronal activity, according...

The Transmitter's reading list: Six upcoming neuroscience books, plus notable titles in 2025

27 Aug 2025

Contributed by Lukas

Dig into an exploration of the fundamental aspects of intelligence, a new textbook about theoretical neuroscience and a memoir about memory research, ...

Long-standing theoretical neuroscience fellowship program loses financial support

26 Aug 2025

Contributed by Lukas

Funding from the Swartz and Sloan Foundations helped bring physicists and mathematicians into neuroscience for more than 30 years.

Should neuroscientists 'vibe code'?

25 Aug 2025

Contributed by Lukas

Researchers are developing software entirely through natural language conversations with advanced large language models. The trend is transforming how...

Adult human cortex does not 'reorganize' after amputation

21 Aug 2025

Contributed by Lukas

The results from a new longitudinal study contradict classic findings in monkeys but may not warrant a rewriting of the textbooks just yet.

Longer fMRI brain scans boost reliability-but only to a point

20 Aug 2025

Contributed by Lukas

Around 30 minutes of imaging per person seems to be the “sweet spot” for linking functional connectivity differences to traits in an accurate and ...

Hitting city streets to record rat behaviors: Q&A with Emily Mackevicius, Ralph Peterson

19 Aug 2025

Contributed by Lukas

Capturing the rodents’ vocalizations and movements in the wild offers an opportunity to study naturalistic behaviors in a complex urban environment,...

Deleting data or stopping its collection will erase years of valuable brain research

18 Aug 2025

Contributed by Lukas

An explosion in open-neuroscience datasets has created a new generation of researchers with expertise in data science. But new federal restrictions in...

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