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Backtable Cardiology

Ep. 16 The Evolution of TAVR: Historical Insights & Future Innovations with Dr. Michael Mack

09 Dec 2025

Description

Transcatheter aortic valve replacement (TAVR) may be a standard cardiac procedure today, but its origin story follows an intriguing tale of courage, innovation and heart. In this episode of BackTable Cardiology, renowned cardiothoracic surgeon Dr. Michael Mack, a global leader in structural heart disease from Baylor Scott White Health, shares the history of TAVR, highlighting its origins, key clinical trials, and the eventual success of TAVR as a primary therapy. --- SYNPOSIS Dr. Michael Mack and host Dr. Sameh Sayfo discuss the early adaptations, challenges, and adoption of TAVR, detailing the collaborative efforts amongst medical professionals that led to its widespread utilization. They also explore the future of valve technology and the importance of multidisciplinary teamwork in advancing cardiovascular care. The discussion concludes with insights into emerging heart technologies and the evolving partnership between different medical specialties. --- TIMESTAMPS 00:00 - Introduction02:27 - Inception of TAVR03:01 - The Global Reach of TAVR11:10 - Placement of Aortic Transcatheter Valves (PARTNER) Trial 19:10 - Advancements in Cardiac Imaging20:35 - Mapping the Next Five Years23:20 - Strides in Aortic Insufficiency 25:16 - Collegiality in Cardiac Care --- RESOURCES How Transcatheter Aortic Valve Implantation (TAVI) Was Born: The Struggle for a New Inventionhttps://pmc.ncbi.nlm.nih.gov/articles/PMC8511628/ Transcatheter Aortic-Valve Implantation for Aortic Stenosis in Patients Who Cannot Undergo Surgeryhttps://www.nejm.org/doi/full/10.1056/NEJMoa1008232 Transcatheter Aortic-Valve Replacement in Low-Risk Patients at Five Yearshttp://nejm.org/doi/full/10.1056/NEJMoa2307447 Dr. Michael Mack Provider Profileshttps://news.bswhealth.com/en-US/photos/michael-mack-md Dr. Sameh Sayfo Provider Profilehttps://www.bswhealth.com/physician/sameh-sayfo

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