Better Sex
281: Permanent Sexual Side Effects from Commonly Prescribed Medications with Dr. Irwin Goldstein
21 Apr 2025
In this episode of the Better Sex Podcast, host sex therapist, Jessa Zimmerman, engages in a thought-provoking conversation with Dr. Irwin Goldstein from the San Diego Sexual Medicine Clinic. They discuss the often overlooked and lasting sexual side effects of widely prescribed medications, including birth control pills, SSRIs, and finasteride (Propecia). Dr. Goldstein explains the mechanisms by which these medications impact sexual health and shares research findings and patient experiences. Listeners are informed about the importance of recognizing these side effects and considering alternative treatments where possible.00:00 Introduction to Better Sex Podcast00:46 Welcoming Dr. Irwin Goldstein01:02 The Hidden Dangers of Common Medications02:52 Deep Dive into Birth Control Pills05:01 Exploring Alternatives to Birth Control Pills05:56 Research Findings on Birth Control Pills06:48 Impact of Birth Control Pills on Androgen Receptors09:32 Long-Term Effects of Birth Control Pills12:33 Introduction to Antidepressants and Sexual Side Effects15:37 Impact of SSRIs on Sexual Health15:52 Mechanisms Behind SSRI-Induced Sexual Dysfunction16:37 Animal Studies and Findings17:53 Persistent Erectile Dysfunction in Young Men18:24 Treatment Options for PSSD19:08 Challenges in Treating PSSD19:56 Gender Differences in PSSD21:13 Introduction to Finasteride and Its Side Effects22:42 Mechanism of Finasteride and Its Impact on Hormones24:29 Health Risks of Finasteride27:42 Conclusion and Final ThoughtsWant to work with Jessa? Visit https://www.intimacywithease.comBio:Dr. Goldstein has been involved with sexual dysfunction research since the late 1970's. He has authored more than 350 publications as well as multiple book chapters and edited 6 textbooks in the field. His interests include penile microvascular bypass surgery, surgery for dyspareunia, sexual health management post cancer treatment, genital dysesthesia/persistent genital arousal disorder, physiologic investigation of sexual function in men and women, and diagnosis and treatment of sexual dysfunction in men and women. Dr. Goldstein is Director of Sexual Medicine at Alvarado Hospital, Clinical Professor of Surgery at University of California, San Diego and practices medicine at San Diego Sexual Medicine. He is also Editor-in-Chief of Sexual Medicine Reviews and past Editor of The Journal of Sexual Medicine. He is a Past President of the International Society for the Study of Women’s Sexual Health and of the Sexual Medicine Society of North America. He holds a degree in engineering from Brown University and received his medical degree from McGill University. The World Association for Sexual Health awarded the Gold Medal to Dr. Goldstein in 2009 in recognition of his lifelong contributions to the field, in 2012 he received the International Society for the Study of Women’s Sexual Health Award for Distinguished Service in Women’s Sexual Health, in 2013 he received the Lifetime Achievement Award from the Sexual Medicine Society of North America, and in 2014 he received the ISSM Lifetime Achievement Award from the International Society for Sexual Medicine. He is happily married to his college sweetheart Sue, and together they have three children and five grandchildren.Want to learn more about my sponsored charity? Charity: Water is committed to providing clean water to every human on the planet, 100% of your contribution will be used directly for water projects around the globe. You can learn more at https://www.bettersexpodcast.com/water.More info and resources:Secret Podcast for the Higher Desire Partner: https://www.intimacywithease.com/hdppodcastSecret Podcast for the Lower Desire Partner: https://www.intimacywithease.com/ldppodcastHow Big a Problem is Your Sex Life? Quiz – https://www.sexlifequiz.comThe Course – https://www.intimacywithease.comThe Book – https://www.sexwithoutstress.comPodcast Website – https://www.intimacywithease.comAccess the Free webinar: Intimacy Made Easy: 3 Secrets to Bridging Libido Differences: https://intimacywithease.com/masterclass
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