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BioBits & Bytes

Next-Gen Immunity: Beyond CAR-T to CAR-M and TCR-T

16 Jul 2025

Description

In this episode of BioBits and Bytes, we dive deep into the next evolution of immune cell therapies. You’ve probably heard of CAR-T cells—genetically engineered T cells that can hunt down and destroy cancer. But what if we could go even further?Welcome to the frontier of next-gen cellular immunotherapy, where scientists are not only engineering T cells, but also macrophages (CAR-M) and TCR-T cells to create smarter, more versatile immune warriors.We’ll explore:How CAR-M therapies reprogram macrophages to eat tumors and reshape the tumor microenvironment.The promise of TCR-T cells, designed to recognize cancer targets even CAR-T can’t reach.Why these innovations could overcome the current limitations of CAR-T therapy—like solid tumors and immune resistance.The challenges in safety, delivery, and manufacturing that lie ahead.Real-world examples from clinical trials and biotech breakthroughs.Whether you're a student, researcher, or just fascinated by the future of cancer therapy, this episode will show you how designer immune cells are reshaping modern medicine—and what the future holds for precision immunotherapy.🔬 Let’s go beyond the T cell and discover the future of immunity.

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