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47. Everything You Need to Know About Semaglutides, GLP-1s, and GIPs

26 Oct 2025

Description

In this episode, Sam sits down with a doctor to answer every burning question we all have about Ozempic, Wegovy, Mounjaro, Rybelsus, Zepbound, and new and emerging semaglutides. Who is a good candidate? Who is not a good candidate? What kind of weight loss is it best for? What are the long-term effects? This episode is jam-packed with information, so you won't want to miss a second. Listen to this episode if you're considering a GLP-1, if you're on a GLP-1, or if you know someone who falls into one of those categories. Key moments: 02:24 What actually is a GLP-1 (Ozempic, Wegovy), and what does it do? 05:14 What about GIP (Mounjaro, Zepbound)? 07:42 The original intended purpose and target audience for semaglutides 09:23 Do you have to stay on it forever to keep the weight off? 15:09 How semaglutides affect your endocrine system 16:27 Do semaglutides help women get pregnant? 19:25 The best and safest way to get off a semaglutide 20:17 Microdosing semaglutides 20:39 Ozempic face and losing muscle tone 22:41 Shortages, high demand, and compounding pharmacies 24:22 Regulated and unregulated formulas 27:26 How semaglutides affect your colon and pancreas 30:23 Long-term effects of using semaglutides (good and bad?) 33:44 Underlying conditions where you should avoid semaglutides 36:44 MB-1 supplements (pill form) - are they legit? 38:51 Upcoming semaglutide formulas and methods of administration 40:10 The stigma surrounding weight loss drugs 41:51 Who is a good candidate for semaglutides? People who want to just drop a couple pounds without exercise, health conditions, obesity, etc. 44:49 If you’ve tried everything else, but you still have 5 lbs. to get rid of… 46:43 Pricing and insurance coverage 50:03 Best practices for people who are taking semaglutides Join ⁠⁠⁠⁠WHOOP⁠⁠⁠⁠. Follow along: Instagram: ⁠⁠⁠⁠⁠⁠⁠www.instagram.com/lifeincapslock⁠⁠⁠⁠⁠⁠⁠  TikTok: ⁠⁠⁠⁠⁠⁠⁠www.tiktok.com/@lifeincapslock⁠⁠⁠⁠⁠⁠⁠  YouTube: ⁠⁠⁠⁠⁠⁠⁠www.youtube.com/@lifeincapslock⁠⁠⁠⁠⁠⁠⁠  Threads: ⁠⁠⁠⁠⁠⁠⁠www.threads.net/@lifeincapslock⁠⁠⁠⁠⁠⁠⁠  Learn more about your ad choices. Visit megaphone.fm/adchoices

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