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Clinically Significant™

Cervical Cancer Screening and Prevention: Guideline Review and Implementation Challenges

25 Nov 2025

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CME Available on the AMA Ed Hub™: https://edhub.ama-assn.org/ama-education/audio-player/10.1001/ama.2025.0002237 What would it take to make cervical cancer a disease of the past? In this episode of Clinically Significant™, host Maylyn Martinez, MD, MSc, sits down with Rebecca Perkins, MD, MSc, and Jodi Abbott, MD, MSc, MHCM, to break down the evolution of cervical cancer screening - from classic Pap smears to the latest advances in HPV testing and self-collection. Discover the evidence behind the current and draft USPSTF guidelines, learn practical strategies for managing abnormal results, and explore how smarter implementation and a focus on reducing disparities in access to screening could help eliminate cervical cancer for good. Tune in for expert insights, high-yield clinical pearls, and actionable ideas that can transform patient care. Learn more about women's health, cervical cancer prevention, and current guidelines on the AMA Ed Hub™. Episode Guest:  • Rebecca Perkins, MD, MSc - Professor, Obstetrics and Gynecology, Tufts University School of Medicine. Clinically Significant™ is hosted by: Jodi Abbott, MD, MSc, MHCM: Professor of ObGyn at Boston University Chobanian & Avedisian School of Medicine and Medical Director of the Education Center Curriculum and Outreach for the American Medical Association (AMA) Maylyn Martinez, MD, MSc: Assistant Professor of Medicine at the University of Chicago and former contributing host, writer, and producer for the JAMA Clinical Reviews podcast Avir Mitra, MD: Associate Professor of Emergency Medicine at NYU Langone and contributing editor at Radiolab (WNYC) CME Info: Accreditation Statement: The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Designation Statement: The AMA designates this Enduring Material activity for a maximum of 0.5 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to:  0.5 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program; ​ 0.5 Self-Assessment points in the American Board of Otolaryngology - Head and Neck Surgery's (ABOHNS) Continuing Certification program;  0.5 MOC points in the American Board of Pediatrics' (ABP) Maintenance of Certification (MOC) program; and  0.5 Lifelong Learning points in the American Board of Pathology's (ABPath) Continuing Certification program  0.5 Credit towards the CME Requirement(s) of the American Board of Surgery's Continuous Certification program It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting MOC credit.  CME Disclosure Statement: Unless noted, all individuals in control of content reported no relevant financial relationships. If applicable, all relevant financial relationships have been mitigated.

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