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Core Memory

The Next Step Toward Understanding The Nature Of Intelligence - EP 49 Sebastian Seung

17 Dec 2025

Description

Well, here we are. It’s brain uploading time.As we’ve just reported, famed neuroscientist Sebastian Seung has created a new start-up called Memazing. The company has set out to build digital brains in software that are based upon the maps of animal brains. Memazing is, in effect, seeking to reverse engineer how animal brains work and to use this information to bring to life a new form of computerized intelligence.This work could lead to, say, more energy efficient AI systems that are modeled on real brains. It could help with aligning AI systems with human intelligence. And it could be a major step toward creating emulations of full human brains and perhaps, one day, making minds uploadable.We get into all of this with Seung on this week’s podcast. We also explore his decades of neuroscience work dedicated to building connectomes, or ultra-detailed schematics of animal brains and all their neurons and synapses.Seung is brilliant and fascinating. Listen and/or watch for yourself.The Core Memory podcast is available on all major platforms and our YouTube channel. Our show is sponsored by Brex, the intelligent finance platform. Like thousands of ambitious, innovative companies, we run on Brex so we can spend smarter and move faster. And you can too. Learn more at www.brex.com/corememoryThe podcast is also made possible by E1 Ventures, which backs the most ambitious founders and start-ups. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.corememory.com/subscribe

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