135 Dr. Ajit Nirmal: How and Why Cancers Spread

When we hear the term tumor or cancer, the image that often comes to mind is a bunch of bad cells next to normal ones, and growing. Like many things, it's just not that simple. How do the normal cells turn bad? Can our immune systems detect the cancer cell and kill it? Why does some, initially successful, chemotherapy stopped working? Why does cancer spread? These are all great questions, since cancers of one kind or another, will affect so many of us either as patients, friends, or loved ones. Well, basic science is providing some critical answers. In today's episode, Therese Markow and Dr. Ajit Nirmal discuss just these questions.     Key Takeaways: If we didn't have an immune system, we'd all get cancer.  Drug resistance continues to be the principal limiting factor to achieving cures in patients with cancer. Once a normal cell has turned cancerous, it is likely dividing much faster than a normal cell. This rapid cell division is error prone, and can lead to accumulation of mutations at a much faster rate.   "I truly believe, with adequate basic understanding of the molecular underpinnings of cancer evolution, and how the tumor microenvironment helps it or promotes it, we will be able to predict the best course of action to target all cancer cells up until the very last one, and consequently to the patient." —  Dr. Ajit Nirmal     Connect with Dr. Ajit Nirmal: Professional Bio: https://scholar.harvard.edu/ajitjohnson/home  LinkedIn: https://www.linkedin.com/in/ajitjohnsonnirmal/      Connect with Therese: Website:   www.criticallyspeaking.net Twitter: @CritiSpeak Email: [email protected]     Audio production by Turnkey Podcast Productions. You're the expert. Your podcast will prove it.  

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