The Beat With Joel Dunning Ep. 111: Allogeneic Mitral Valve Transplant

This week on The Beat, CTSNet Editor-in-Chief Joel Dunning speaks with Dr. David Kalfa, the incoming Chief of Pediatric Cardiac Surgery and Co-Director of the Heart Institute at Nicklaus Children’s Hospital in Miami, about allogeneic mitral valve transplants. Chapters 00:00 Intro 01:46 Interview Preview 02:54 MV Surgery After Failed Intervention 07:46 Tears Predict Outcomes After Hemi-Arch 10:32 Pain Catastrophizing Scale 14:27 ARR w Stentless Biopros, Sex Difference 16:38 Open Implant TAV via Redo Sternotomy 19:05 Repeat Sternotomy w Completion Unifocaliz 21:07 Direct Aortic Impella 5.5 in PC Shock 25:16 Dr. Kalfa Interview, AMV Transplant 39:58 Upcoming Events 41:26 Closing They discuss methods for obtaining a mitral valve for transplantation, and topics such as immunosuppression, aortic coagulation, and the progress that has been made in this field. They also explore how to perform a living allogeneic heart valve transplant and the future of this technique.   Joel also highlights recent JANS articles on mitral valve surgery after failed transcatheter intervention for mitral regurgitation, whether distal anastomotic new entry tears predict long-term outcomes after hemiarch repair for DeBakey I aortic dissection, using a pain catastrophizing scale as a predictor for acute postoperative pain following video-assisted thoracoscopic surgery lobectomy, and sex difference in aortic root replacement with a stentless bioprosthesis.  In addition, Joel explores an open implantation of a transcatheter aortic valve via redo sternotomy, mitral valve replacement, and tricuspid valve repair in a high-risk patient, repeat sternotomy with completion unifocalization and extensive pulmonary arterial reconstruction in ToF/PA/MAPCAs, and direct aortic Impella 5.5 in post-cardiotomy shock. Before closing, Joel highlights upcoming events in CT surgery.    JANS Items Mentioned  1.) Mitral Valve Surgery After Failed Transcatheter Intervention for Mitral Regurgitation: Techniques, Challenges, and Outcomes  2.) Distal Anastomotic New Entry Tears Predict Long-Term Outcomes After Hemi-Arch Repair for DeBakey I Aortic Dissection  3.) Pain Catastrophizing Scale as a Predictor for Acute Postoperative Pain Following Video-Assisted Thoracoscopic Surgery Lobectomy  4.) Sex Difference in Aortic Root Replacement With a Stentless Bioprosthesis  CTSNET Content Mentioned  1.) Open Implantation of a Transcatheter Aortic Valve via Redo Sternotomy, Mitral Valve Replacement, and Tricuspid Valve Repair in a High-Risk-Patient  2.) Challenging Pulmonary Arterial Reconstruction: Repeat Sternotomy With Completion Unifocalization and Extensive Pulmonary Arterial Reconstruction in ToF/PA/MAPCAs   3.) Direct Aortic Impella 5.5 in Post-Cardiotomy Shock  Other Items Mentioned  1.) Allogeneic Mitral Valve Transplant: Historical Precedent, Current Considerations, and Future Implementation  2.) Cardiac Surgical Arrest—An International Conversation, Part 1  3.) Winners of the 2025 CTSNet Instructional Video Competition  4.) Career Center   5.) CTSNet Events Calendar  Disclaimer The information and views presented on CTSNet.org represent the views of the authors and contributors of the material and not of CTSNet. Please review our full disclaimer page here.

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