The Microscopic Chemical Warfare Of Antibiotics

Research isn't always conducted in a laboratory. Dr. Brian T. Murphy runs a research program that takes him all around the world collecting aquatic microorganisms, en route to the discovery and development of new antibiotics. On this podcast, Dr. Murphy explains how antibiotics work and the importance of discovering new ones, as well as detailing some of the exotic underwater adventures involved in his line of work.Ongoing projects in Dr. Murphy's lab merge the identification of small molecules with marine microbiology, molecular biology, genomics, and bioinformatics. To date, his lab has built a collection of over 1,500 aquatic bacteria and are using them to generate small molecule libraries that they screen against bacterial pathogens and cancers. The lab is also innovating the way drug discovery libraries are managed to make them more intuitive and efficient.Antibiotics research crowdsourcing programs:Great Lakes Freshwater Sponge Ecology And Drug-Discovery (Murphy Lab project)University of Oklahoma's Citizen Science Soil Collection ProgramDrugs from Dirt (US)Swab and Send (UK)Small World InitiativeAdditional scientific resources discussed:Murphy Lab UIC websiteCurrent Murphy Lab projectsFeature on Murphy Lab in Toronto StarBill and Melinda Gates FoundationTB AllianceMurphy Lab on TwitterFollow Curiosity Daily on your favorite podcast app to get smarter with Cody Gough and Ashley Hamer — for free! Still curious? Get exclusive science shows, nature documentaries, and more real-life entertainment on discovery+! Go to https://discoveryplus.com/curiosity to start your 7-day free trial. discovery+ is currently only available for US subscribers. Full episode transcript here: https://curiosity-daily-4e53644e.simplecast.com/episodes/the-microscopic-chemical-warfare-of-antibiotics Hosted on Acast. See acast.com/privacy for more information.

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