How AI Learned to Write Perfect Pharmaceutical Protocols

Medium: https://medium.com/@jsmith0475/how-ai-learned-to-write-perfect-pharmaceutical-protocols-4487ba139f72 "How AI Learned to Write Perfect Pharmaceutical Protocols," by Dr. Jerry A. Smith, presents a research paper detailing a novel Artificial Intelligence (AI) architecture designed to generate analytical protocols for pharmaceutical testing that comply with Good Manufacturing Practice (GMP) regulations. This system addresses the slow, expensive process of human-led method development by using a multi-agent generation approach, creating five protocol variants at varying levels of creativity, which are then evaluated and selected through a triadic judge system and a four-round tournament elimination. Critical to its success is a cognitive anchoring framework that constrains the Large Language Model (LLM) to regulatory-compliant outputs, preventing the common problem of AI "hallucinations." The authors demonstrate that the AI-generated protocols achieved a +2.1% quality improvement over deterministic methods and maintained 93.54% similarity to GMP compliance while drastically cutting time and cost.

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