Improving the Mitochondrial-Microbiome Connection for Optimal Health with Jason Prall

In this episode, Dr. Jockers explores with Jason Prall how mitochondrial health and the gut microbiome are deeply connected, shaping energy, inflammation, and long-term resilience. You'll learn why mitochondria are far more than energy producers and how their communication drives whole-body health.   In this episode, you'll discover how the microbiome helps translate food into signals that influence mitochondrial function, metabolism, and cellular repair. Jason breaks down why diversity in the gut matters and how everyday choices quietly shape this internal dialogue.   In this episode, you'll hear practical insights on how sleep, light exposure, movement, fasting, and stress act as signals that either strengthen or weaken this mitochondrial–microbiome connection. The conversation leaves space to rethink how small lifestyle shifts can create powerful biological change.     In This Episode:  00:00 Introduction to Human and Mitochondrial DNA 04:06 Deep Dive into Mitochondria and Aging 14:01 Understanding the Gut Microbiome 25:38 Environmental Factors Affecting Health 29:19 Mindfulness and Detoxification 29:55 Impact of Thoughts on Health 31:06 Personalized Health Approaches 31:39 Universal Health Strategies 33:43 Importance of Sleep 37:19 Exercise and Movement 41:07 Fasting and Meal Timing 45:48 Stress and Recovery Balance 48:42 Final Thoughts and Resources     If you want practical, natural strategies to balance your hormones, heal your gut, boost your energy, and slow aging, don't miss The Dr. Josh Axe Show. Dr. Axe blends ancient wisdom with cutting-edge science and brings on world-class experts for unfiltered conversations you won't hear anywhere else. Transform your health from the inside out and subscribe to The Dr. Josh Axe Show, with new episodes every Monday and Thursday.   Support glowing skin, stronger joints, better digestion, and deeper sleep with Paleovalley's 100% Grass-Fed Bone Broth Protein. Unlike most brands that use hides and skins, Paleovalley slow-simmers real beef bones to extract collagen, glycine, and key amino acids that boost metabolism and reduce inflammation. Each scoop delivers 15 grams of collagen and the clinical dose of glycine for better sleep. Get 15% off at paleovalley.com/jockers.     "Every disease involves mitochondria—when mitochondrial function fails, the body breaks down."      Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio     Resources: Paleovalley Bone Broth Protein: Save 15% on grass-fed bone broth protein at paleovalley.com/jockers.   Connect with Jason Prall: Book:  https://amzn.to/3YC78Wt Website:  humanlongevityfilm.com, beyondlongevitybook.com   Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/ 

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