Episode 75: Aging as an Evolutionary Program with Josh Mitteldorf

As FxMed docs, we’re committed to working with the body’s own capacity for health. Dr. Josh Mitteldorf offers a contrarian strategy, one which he says is grounded in a new breed of evolutionary medicine. He tells us that diseases of old age are qualitatively different from the diseases we get when we’re younger, different because in old age, our bodies are part of the problem, not part of the solution. Aging, says Josh, is the body deliberately destroying itself (for the sake of the population), via inflammation and apoptosis and autoimmune diseases. In this interview, Josh and I find common ground talking about hormesis. In Josh’s theory, the fact that the body lives longer when stressed (e.g. caloric restriction) is proof that the body isn’t trying its hardest to stay young when it’s not stressed. It may sound like philosophy, but there are real consequences for the future of medicine. These are challenging ideas, so I’m eager to hear what you think, and be sure to leave a review wherever you listen to New Frontiers! Thank you! ~DrKF

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