#43: oxycodone+acetaminophen (Percocet) | Treating Moderate to Severe Pain

Oxycodone+acetaminophen (APAP) is an analgesic combination product also known as Percocet. When dosing for Percocet one should consider also prescribing naloxone if there is a possible risk of opioid overdose or accidental ingestion. It is also very important to note that the lowest effective dose at the shortest effect duration should be used. Dosing for Percocet is based on the oxycodone component but limited by the APAP component. A general dosing range is 2.5-10 mg oxycodone PO q6h prn. Do not exceed 1 gram of APAP in 4 hours and 4 grams of APAP in 24 hours. There are a large amount of black box warnings and it is highly suggested to review them all. Some of note are for addiction/abuse/misuse, respiratory depression, and hepatotoxicity. Patients that should not use this medication are those with severe asthma or similar breathing problems, stomach or intestine blockage, drug or alcohol addiction, or problems with urination/thyroid/pancreas/gallbladder.  Go to DrugCardsDaily.com for episode show notes which consist of the drug summary, quiz, and link to the drug card for FREE! Please SUBSCRIBE, FOLLOW, and RATE on Spotify, Apple Podcasts, or wherever your favorite place to listen to podcasts are. The main goal is to go over the Top 200 Drugs with the occasional drug of interest. Also, if you’d like to say hello, suggest a drug, or leave some feedback I’d really appreciate hearing from you! Leave a voice message at anchor.fm/drugcardsdaily or find me on twitter @drugcardsdaily

There are no comments yet.

Please log in to write the first comment.